DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Set2 and CG4565

DIOPT Version :9

Sequence 1:	NP_572888.2	Gene:	Set2 / 32301	FlyBaseID:	FBgn0030486	Length:	2362	Species:	Drosophila melanogaster
Sequence 2:	NP_001097743.1	Gene:	CG4565 / 41303	FlyBaseID:	FBgn0037841	Length:	269	Species:	Drosophila melanogaster

Alignment Length:	283	Identity:	73/283 - (25%)
Similarity:	116/283 - (40%)	Gaps:	65/283 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  1312 MDEQLAELA---------NIEAINEQFLR-SEGLNTFQLLKENFYR-----CARQVSQENAEMQC 1361
            |||  :|.|         .::.|.|..|. |:|...|:.|.:.:..     |..:.:.||:|:
  Fly     1 MDE--SETAPNDDYEHPDGLDYILESVLMPSDGSKEFKFLADEYNSVLLNPCHCKGACENSEV-- 61

  Fly  1362 DCFLTGDEEAQGHLSCGAGCINRML---MIECGPLCS---NGARCTNKRFQQHQCWPCRVFRTE- 1419
             |...|..|   ....|:..|.|..   :|||..:|.   |  .|:|:...........:|.:.
  Fly    62 -CAHGGQYE---FTEDGSELILRNSANPVIECNDMCKCCRN--TCSNRLVYSGPRKHLEIFDSPV 120

  Fly  1420 --KKGCGITAELLIPPGEFIMEYVGEVIDSEEFERRQH---------------LYSKDRNRHYYF 1467
              .||...||:  |..|.:|.||.||::...|...|.|               .|:.|:.:..
  Fly   121 YGSKGLRTTAK--ITKGGYICEYAGELLTVPEARSRLHDNEKLGLMNYILVLNEYTSDKKQQV-- 181

  Fly  1468 MALRGEAVIDATSKGNISRYINHSCDPNAETQKWTVNGEL-RIGFFSVKPIQPGEEITFDY---- 1527
                  .::|.:.:|||.||:||||:||.......::..: :||.|:.:.|...||:.|.|
  Fly   182 ------TIVDPSRRGNIGRYLNHSCEPNCHIAAVRIDCPIPKIGIFAARDIAAKEELCFHYGGEG 240

  Fly  1528 QYLRYGRDAQRCYCEAANCRGWI 1550
            ||.:. ...:.|.|.|:.|.|::
  Fly   241 QYKKM-TGGKTCLCGASKCTGFM 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set2	NP_572888.2	AWS	1358..1410	CDD:197795	14/57 (25%)
		SET	1414..1533	CDD:214614	39/141 (28%)
		PostSET	1535..1551	CDD:214703	5/16 (31%)
		WW	2014..2043	CDD:278809
		SRI	2270..2348	CDD:285448
CG4565	NP_001097743.1	Pre-SET	10..103	CDD:282838	23/100 (23%)
CG4565	NP_001097743.1	SET	111..239	CDD:214614	37/137 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467627
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840