DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Set2 and Suv39h2

DIOPT Version :9

Sequence 1:	NP_572888.2	Gene:	Set2 / 32301	FlyBaseID:	FBgn0030486	Length:	2362	Species:	Drosophila melanogaster
Sequence 2:	XP_038951911.1	Gene:	Suv39h2 / 364785	RGDID:	1306969	Length:	511	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	83/243 - (34%)
Similarity:	107/243 - (44%)	Gaps:	42/243 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1344 NFYRCARQVS-QENAEMQCDCFLTGDEEAQGHLSCGAGCI-----NRMLMI-------ECGPLCS 1395
            |.||.|..:: ...|...|.|.....|:.   ....||.:     ||.:.|       ||...|.
  Rat   274 NEYRPAPGITLNSEATFGCSCTNCFFEKC---CPAEAGVVLAYNKNRQIKIQPGTPIYECNSRCR 335

  Fly  1396 NGARCTNKRFQQHQCWPCRVFRTEKKGCGITAELL--IPPGEFIMEYVGEVIDSEEFERRQHLYS 1458
            .|..|.|:..|:...:...:||| ..|||...:.|  |....|:||||||||.|||.|||..||
  Rat   336 CGPDCPNRIVQKGTQYSLCIFRT-SNGCGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQLY- 398

  Fly  1459 KDRNRHYYFMAL---RGEAVIDATSKGNISRYINHSCDPNAETQKWTVNG---EL-RIGFFSVKP 1516
             |.....|...|   ..|..:||...||:|.::|||||||.:.....::.   .| ||..||.:.
  Rat   399 -DNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFSVFIDNLDTRLPRIALFSTRT 462

  Fly  1517 IQPGEEITFDYQYLRYG--------------RDAQRCYCEAANCRGWI 1550
            |:.|||:|||||....|              |...:|.|.|..|||::
  Rat   463 IKAGEELTFDYQMKGSGELSSDSIDYSPARKRVRTQCKCGAETCRGYL 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set2	NP_572888.2	AWS	1358..1410	CDD:197795	15/63 (24%)
		SET	1414..1533	CDD:214614	55/127 (43%)
		PostSET	1535..1551	CDD:214703	6/16 (38%)
		WW	2014..2043	CDD:278809
		SRI	2270..2348	CDD:285448
Suv39h2	XP_038951911.1	CD_SUV39H1_like	148..196	CDD:349289
Suv39h2	XP_038951911.1	SET_SUV39H2	268..510	CDD:380930	83/241 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352021
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840