Protein Alignment Set2 and set-32

DIOPT Version :10

• Sequence 1: NP_572888.2
• Gene: Set2 / 32301
• FlyBaseID: FBgn0030486
• Length: 2362
• Species: Drosophila melanogaster
• Sequence 2: NP_492529.2
• Gene: set-32 / 183391
• WormBaseID: WBGene00008062
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 527
• Identity: 106/527 - (20%)
• Similarity: 181/527 - (34%)
• Gaps: 156/527 - (29%)

  Fly  1117 LQTAGKKRGRKEGKESLSRQ--NSLDSSSSASQGAPKKKALKSAEILSAALLETESSESTSSGSK 1179
            :.:..|.|.:|:.::..||.  ..:.:|:.....||..||.:...|..||     ..|...:..|
 Worm     1 MSSKSKSRTKKKLRQHSSRGPITEMLASNMCIFEAPPFKAEQDFPIYLAA-----GYEERRTFLK 60

  Fly  1180 MSRWDVQTSPELEAANPFGDIAKFIEDGVNLLKR--------------DKVDED----------Q 1220
            .|...|:|.|         |:..:.:..|.:|.:              .|.|||          |
 Worm    61 ESACLVETKP---------DVENYSQSHVKVLNKIRNDPHLNGNWKLLPKYDEDVKGTMMRILGQ 116

  Fly  1221 R---KEGQD-EVKREADPEEDEFAQRVANMETPATTPTPSPTQSNPEDSASTTTVLKELETGGGV 1281
            |   .:|:: |:....|..:|              .|..|||...|.
 Worm   117 RAMISQGREHEISTCPDSGQD--------------VPLLSPTYITPR------------------ 149

  Fly  1282 RRSHRIKQKPQGPRASQGRGVASVALAPISM---DEQLAELANIEAINEQFLRSEGLNTFQLLKE 1343
               .||       |.::.....::.:.|:..   ||:|..:...:.:..::..:..||...  ..
 Worm   150 ---KRI-------RVTENLTFNTLDIVPVYSDLPDEKLTSIQIPDTLLFEYTDTNVLNPCS--AR 202

  Fly  1344 NFYRCARQVSQENAEMQCDCFLTG----------------DEEAQG-------H----------- 1374
            |..:......:|...::|||..:.                :::.||       |
 Worm   203 NIAKACIMSQKEENTIRCDCCSSNPIVPCYENENCPCYKLNQKLQGLQINSSSHPPTKFASFDPV 267

  Fly  1375 -LSCGAGCINRMLMIECGPLCSNGARCTNKR--FQQHQCWPCRVFRT-EKKGCGITAELLIPPGE 1435
             .|......:|.:...|...|.....|||..  ....:.:|..::|: |..|.|:.:.:|||.|.
 Worm   268 MFSNSNSTFDRCIGFSCSEACGCKGNCTNNSLLILNKKLFPLEIYRSNENVGFGLRSSVLIPAGT 332

  Fly  1436 FIMEYVGEVIDSEEFERRQHLYS-----KDRN---------------RHYYFMALRGEAVIDATS 1480
            .::|:.||:::..:.:|....|:     ||.:               :.:.......|..||..:
 Worm   333 AVLEFTGEIVERNQLDRDSQDYAYQLTDKDNSNWRRLLDTMKFSDDYKKFLKKLSYEEFFIDPKA 397

  Fly  1481 KGNISRYINHSCDPNAET----QKWTVNGELRIGFFSVKPIQPGEEITFDYQYLRYGRD--AQRC 1539
            |||:.|.|.|||.||.|.    ||......:.:.|.|:..|.||..:|.||.| .|.::  ..:|
 Worm   398 KGNVGRMICHSCSPNLEIVRVYQKGLSPAHVHLVFISLLNIYPGTPLTMDYGY-NYMKNHLNGKC 461

  Fly  1540 YCEAANC 1546
            .|.:..|
 Worm   462 ECGSFAC 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Set2	NP_572888.2	valS	<709..832	CDD:237855
		AWS	1358..1410	CDD:197795	13/88 (15%)
		SET_SETD2	1410..1551	CDD:380949	45/164 (27%)
		WW	2014..2043	CDD:459800
		SRI	2266..2355	CDD:462404
set-32	NP_492529.2	SET	307..455	CDD:214614	42/148 (28%)