Protein Alignment Set2 and set-1

DIOPT Version :10

• Sequence 1: NP_572888.2
• Gene: Set2 / 32301
• FlyBaseID: FBgn0030486
• Length: 2362
• Species: Drosophila melanogaster
• Sequence 2: NP_001022796.1
• Gene: set-1 / 175918
• WormBaseID: WBGene00004781
• Length: 242
• Species: Caenorhabditis elegans
• Alignment Length: 304
• Identity: 63/304 - (20%)
• Similarity: 107/304 - (35%)
• Gaps: 107/304 - (35%)

  Fly  1232 ADPEEDEFAQRVANMETPATTPTPSPTQSNPEDSASTTTVLKELETGGGVRRSHRIKQKPQGPRA 1296
            |.|..|     :.|.|.|::..:.|.:......|.:|                          |:
 Worm    21 ASPSSD-----IENSENPSSLASHSSSSGRMTPSKNT--------------------------RS 54

  Fly  1297 SQGRGVASVALAPISMDEQLAELANIEAINEQFLRSEGLNTFQLLKENFYRCARQVSQENAEMQC 1361
            .:|..|..|:      :.::.|.                  ||:.:.| .:.::|:|.|......
 Worm    55 RKGVSVKDVS------NHKITEF------------------FQVRRSN-RKTSKQISDEAKHALR 94

  Fly  1362 DCFLTGDEEAQGHLSCGAGCINRMLMIECGPLCSNGARCTNKRFQQHQCWPCRVFRTEKKGCGIT 1426
            |..|.|                                 ||:|..:       |::...||.||.
 Worm    95 DTVLKG---------------------------------TNERLLE-------VYKDVVKGRGIR 119

  Fly  1427 AELLIPPGEFIMEYVGEVIDSEEFERRQHLYSKDR---NRHYYFMALRGEAVIDATS----KGNI 1484
            .::....|:|::||.|.:::..|.:..:..||.|.   :..|:|.....:..||||.    ||
 Worm   120 TKVNFEKGDFVVEYRGVMMEYSEAKVIEEQYSNDEEIGSYMYFFEHNNKKWCIDATKESPWKG-- 182

  Fly  1485 SRYINHS-CDPNAETQKWTVNGELRIGFFSVKPIQPGEEITFDY 1527
             |.|||| ..||.:|:...::|...:...:.:.|..|||:.:||
 Worm   183 -RLINHSVLRPNLKTKVVEIDGSHHLILVARRQIAQGEELLYDY 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Set2	NP_572888.2	valS	<709..832	CDD:237855
		AWS	1358..1410	CDD:197795	6/51 (12%)
		SET_SETD2	1410..1551	CDD:380949	37/126 (29%)
		WW	2014..2043	CDD:459800
		SRI	2266..2355	CDD:462404
set-1	NP_001022796.1	SET_SETD8	87..228	CDD:380926	44/182 (24%)