Protein Alignment CG1998 and FA2H

DIOPT Version :9

• Sequence 1: NP_001285210.1
• Gene: CG1998 / 32300
• FlyBaseID: FBgn0030485
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_077282.3
• Gene: FA2H / 79152
• HGNCID: 21197
• Length: 372
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 57/275 - (20%)
• Similarity: 94/275 - (34%)
• Gaps: 92/275 - (33%)

  Fly   139 WDKFIDSFGDEPMVLWVFGTTIFTMLVYWTVGTLYTFMDLTNRPACLRKYKIQPGTNEPVE---- 199
            |||        .:|.|       ...:.|.||.|....|         ::..||.| .|:.
Human   119 WDK--------DLVDW-------RKPLLWQVGHLGEKYD---------EWVHQPVT-RPIRLFHS 158

  Fly   200 --VRRLLKVIWCVVCNQIFVGIPLA-YASYRLMEIRGLSDIRDLPTFHWVCFELTVCI------- 254
              :..|.|.:|..|   ..:.:||. |.|:.........::|...:|   ..|.||.:
Human   159 DLIEGLSKTVWYSV---PIIWVPLVLYLSWSYYRTFAQGNVRLFTSF---TTEYTVAVPKSMFPG 217

  Fly   255 ----------LMEELGFYYSHRLLHHKH----------IYKYIHKQHHEWTAPISVTAIYCHPIE 299
                      |:|    |..||.|.|..          ::..:|.|||:  ||...:.:...|:.
Human   218 LFMLGTFLWSLIE----YLIHRFLFHMKPPSDSYYLIMLHFVMHGQHHK--APFDGSRLVFPPVP 276

  Fly   300 HIFSNLLPPFLGVFLMGSHV----ATAWLWFALAILSTLNAHSGYHLPFFPSPEAHDF------H 354
               ::|:   :|||.:...:    |.....||..:|..:.....::...|.||....:      |
Human   277 ---ASLV---IGVFYLCMQLILPEAVGGTVFAGGLLGYVLYDMTHYYLHFGSPHKGSYLYSLKAH 335

  Fly   355 HLKFN-----NCFGV 364
            |:|.:     :.||:
Human   336 HVKHHFAHQKSGFGI 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1998	NP_001285210.1	ERG3	<245..374	CDD:225546	33/162 (20%)
		FA_hydroxylase	250..374	CDD:282034	32/157 (20%)
FA2H	NP_077282.3	Cyt-b5	15..85	CDD:278597
		FA_hydroxylase	124..366	CDD:294712	54/262 (21%)
		ERG3	<210..367	CDD:225546	30/153 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3000
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900