DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1998 and Msmo1

DIOPT Version :9

Sequence 1:	NP_001285210.1	Gene:	CG1998 / 32300	FlyBaseID:	FBgn0030485	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_079712.1	Gene:	Msmo1 / 66234	MGIID:	1913484	Length:	293	Species:	Mus musculus

Alignment Length:	265	Identity:	84/265 - (31%)
Similarity:	128/265 - (48%)	Gaps:	36/265 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 WQSQWDKFIDSFGDEPMVLWVFGTTIFTMLVYWTV---GTLYTFMDLTNRPACLRKYKIQPGTNE 196
            :::.|...:|::....:..|  |:.|....:|:..   |.|:.|:..      :||||||....|
Mouse    33 FKNAWVYMLDNYTKFQIATW--GSLIVHEAIYFLFSLPGFLFQFIPY------MRKYKIQKDKPE 89

  Fly   197 PVEVR-RLLKVIWCVVCNQIFVGIPLAYASYRLMEIRGLS-DIRDLPTFHWVCFELTVCILMEEL 259
            ..|.: :.||.|   :.|..|:.:||...:|...|...:. |...:|.::........|.::|:.
Mouse    90 TFEGQWKCLKKI---LFNHFFIQLPLICGTYYFTEFFNIPYDWERMPRWYLTLARCLGCAVIEDT 151

  Fly   260 GFYYSHRLLHHKHIYKYIHKQHHEWTAPISVTAIYCHPIEHI-----FSNLLPPFLGVFLMGSHV 319
            ..|:.|||||||.|||||||.|||:.||..:.|.|.||:|.:     |      |:|:.|:..||
Mouse   152 WHYFLHRLLHHKRIYKYIHKVHHEFQAPFGIEAEYAHPLETLILGTGF------FIGIVLLCDHV 210

  Fly   320 ATAWLWFALAILSTLNAHSGYHL--------PFFPSPEAHDFHHLKF-NNCFGVLGVLDRLHGTD 375
            ...|.|..:.:|.|::.||||.:        ||:.....|||||:.| .|........|:|.|||
Mouse   211 ILLWAWVTIRLLETIDVHSGYDIPLNPLNLVPFYTGARHHDFHHMNFIGNYASTFTWWDKLFGTD 275

  Fly   376 SLFRA 380
            :.:.|
Mouse   276 AQYHA 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1998	NP_001285210.1	ERG3	<245..374	CDD:225546	52/142 (37%)
CG1998	NP_001285210.1	FA_hydroxylase	250..374	CDD:282034	52/137 (38%)
Msmo1	NP_079712.1	FA_hydroxylase	143..274	CDD:397991	52/136 (38%)
		Histidine box-1	157..161		3/3 (100%)
		Histidine box-2	170..174		2/3 (67%)
		Histidine box-3	249..255		4/5 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3000
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R751
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840