DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1998 and CG11162

DIOPT Version :9

Sequence 1:	NP_001285210.1	Gene:	CG1998 / 32300	FlyBaseID:	FBgn0030485	Length:	406	Species:	Drosophila melanogaster
Sequence 2:	NP_572910.1	Gene:	CG11162 / 32325	FlyBaseID:	FBgn0030509	Length:	278	Species:	Drosophila melanogaster

Alignment Length:	255	Identity:	118/255 - (46%)
Similarity:	170/255 - (66%)	Gaps:	5/255 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 WGASGDFWQSQWDKFIDSFGDEPMVLWVFGTTIFTMLVYWTVGTLYTFMDLTNRPACLRKYKIQP 192
            |..|||:.|.:|...:|:.|:|...|||.|:|:...:|||....::|.||:||||..||||||||
  Fly     8 WTQSGDYLQDKWTLLLDTVGEESWRLWVVGSTVVIFIVYWLYAGIFTLMDITNRPRFLRKYKIQP 72

  Fly   193 GTNEPVEVRRLLKVIWCVVCNQIFVGIPLAYASYRLM-EIRGLSDIRDLPTFHWVCFELTVCILM 256
            |.||||.:.:|...:..|:.|...|...:::..|..: :.....|||.||||.....:|.|.:::
  Fly    73 GQNEPVNLAKLWHAVKVVLFNLTVVNFLVSWVVYEFVYKSENSQDIRVLPTFKRSLRDLVVFVVL 137

  Fly   257 EELGFYYSHRLLHHKHIYKYIHKQHHEWTAPISVTAIYCHPIEHIFSNLLPPFLGVFLMGSHVAT 321
            ||:.|||:||||||:.:|||:||:||||||||:...:|.||:||:.:||||....:.::|:|||.
  Fly   138 EEIMFYYAHRLLHHRSVYKYVHKKHHEWTAPIAAITLYAHPVEHVLANLLPVATSIAILGTHVAL 202

  Fly   322 AWLWFALAILSTLNAHSGYHLPFFP-SPEAHDFHHLKFNNCFGVLGVLDRLHGTDSLFRA 380
            |::.|||||:::::.|:||..|:.. |...||:||.|||..:||||.||:||||   :||
  Fly   203 AYVIFALAIINSMSDHTGYSFPWSAGSVRFHDYHHAKFNYNYGVLGFLDKLHGT---YRA 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1998	NP_001285210.1	ERG3	<245..374	CDD:225546	65/129 (50%)
CG1998	NP_001285210.1	FA_hydroxylase	250..374	CDD:282034	65/124 (52%)
CG11162	NP_572910.1	ERG3	31..269	CDD:225546	109/232 (47%)
CG11162	NP_572910.1	FA_hydroxylase	131..256	CDD:282034	65/124 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448727
Domainoid	1	1.000	99	1.000	Domainoid score	I2371
eggNOG	1	0.900	-	-		E1_COG3000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	135	1.000	Inparanoid score	I1831
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1321777at2759
OrthoFinder	1	1.000	-	-		FOG0002076
OrthoInspector	1	1.000	-	-		mtm1069
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11863
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R751
SonicParanoid	0	0.000	Not matched by this tool.
	10	9.930