Protein Alignment CG1998 and FAXDC2

DIOPT Version :10

• Sequence 1: NP_572887.1
• Gene: CG1998 / 32300
• FlyBaseID: FBgn0030485
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_115761.2
• Gene: FAXDC2 / 10826
• HGNCID: 1334
• Length: 333
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 150/323 - (46%)
• Similarity: 209/323 - (64%)
• Gaps: 1/323 - (0%)

  Fly    80 GSPLQNWDDARTADVWLSSLHSVIFIITCALAAFILFRNVLTWHLQSFWGASGDFWQSQWDKFID 144
            |..|.|....:...:| .|:....||:...|.:|:.|.|.:|||||.||||||.|||:||::.:.
Human     6 GHMLHNEKSKQEGHIW-GSMRRTAFILGSGLLSFVAFWNSVTWHLQRFWGASGYFWQAQWERLLT 69

  Fly   145 SFGDEPMVLWVFGTTIFTMLVYWTVGTLYTFMDLTNRPACLRKYKIQPGTNEPVEVRRLLKVIWC 209
            :|..:..:|:..|......|.:|:...|...:|.|.:|..:.:|:||.|.||||:..:|.:.|..
Human    70 TFEGKEWILFFIGAIQVPCLFFWSFNGLLLVVDTTGKPNFISRYRIQVGKNEPVDPVKLRQSIRT 134

  Fly   210 VVCNQIFVGIPLAYASYRLMEIRGLSDIRDLPTFHWVCFELTVCILMEELGFYYSHRLLHHKHIY 274
            |:.||..:..|:....|..::.......|:||||||...||.:..|:||:.||||||||||...|
Human   135 VLFNQCMISFPMVVFLYPFLKWWRDPCRRELPTFHWFLLELAIFTLIEEVLFYYSHRLLHHPTFY 199

  Fly   275 KYIHKQHHEWTAPISVTAIYCHPIEHIFSNLLPPFLGVFLMGSHVATAWLWFALAILSTLNAHSG 339
            |.|||:||||||||.|.::|.|||||..||:||..:|..:||||:::..:||:||::.|..:|.|
Human   200 KKIHKKHHEWTAPIGVISLYAHPIEHAVSNMLPVIVGPLVMGSHLSSITMWFSLALIITTISHCG 264

  Fly   340 YHLPFFPSPEAHDFHHLKFNNCFGVLGVLDRLHGTDSLFRATKSYARHIMMLSFKPPRDAFPD 402
            |||||.||||.||:||||||.|:|||||||.|||||::|:.||:|.||:::|.|.|..::.||
Human   265 YHLPFLPSPEFHDYHHLKFNQCYGVLGVLDHLHGTDTMFKQTKAYERHVLLLGFTPLSESIPD 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1998	NP_572887.1	FA_hydroxylase	250..374	CDD:397991	77/123 (63%)
FAXDC2	NP_115761.2	FA_hydroxylase	175..299	CDD:397991	77/123 (63%)