DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstT4 and Gstt2

DIOPT Version :9

Sequence 1:	NP_572886.2	Gene:	GstT4 / 32299	FlyBaseID:	FBgn0030484	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	XP_011241675.1	Gene:	Gstt2 / 14872	MGIID:	106188	Length:	251	Species:	Mus musculus

Alignment Length:	231	Identity:	71/231 - (30%)
Similarity:	116/231 - (50%)	Gaps:	17/231 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LKFYFDFLNQSSRALYILLEASKIPFEAIPISMLKGEHLTGEFRDNVNRFRKLPAITDHGYQLSE 69
            |:.|.|.|:|.|||:||..:.:.|||:...:.:|||:|::.:| ..||...|:|.:.|..:.|:|
Mouse     3 LELYLDLLSQPSRAVYIFAKKNGIPFQTRTVDILKGQHMSEQF-SQVNCLNKVPVLKDGSFVLTE 66

  Fly    70 -------NVAIFRHLAREKLVPEHWYPRRHLGRSRIDEYLAWQQTNMGVATTEYFQQKWLVPYLQ 127
                   :.||..:|:.:..|.:||||.....|:::.|||.|...|:..........|.|.|.:.
Mouse    67 SPSSMIPSTAILIYLSSKYQVADHWYPADLQARAQVHEYLGWHADNIRGTFGVLLWTKVLGPLIG 131

  Fly   128 KTRPADNAVNLASKQLEHTLNEFEQLFLNSRKFMMGDNISYADLSAICEIDQPKSIGYNAFQNRN 192
            ...|.:. |.....::...|.:.|..||..|.|::|..::.|||.::.|:.||.::|||.|:.|.
Mouse   132 VQVPQEK-VERNRDRMVLVLQQLEDKFLRDRAFLVGQQVTLADLMSLEELMQPVALGYNLFEGRP 195

  Fly   193 KLARWYETVREELGPHYKE--------VLGEFEAKL 220
            :|..|.|.|...||....:        :||:...|:
Mouse   196 QLTAWRERVEAFLGAELCQEAHSTILSILGQAAKKM 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstT4	NP_572886.2	GST_N_Theta	5..80	CDD:239348	28/81 (35%)
GstT4	NP_572886.2	GST_C_Theta	95..220	CDD:198292	37/132 (28%)
Gstt2	XP_011241675.1	GST_N_Theta	3..85	CDD:239348	28/82 (34%)
Gstt2	XP_011241675.1	GST_C_Theta	98..223	CDD:198292	35/125 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	61	1.000	Domainoid score	I10389
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4379
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54888
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm8775
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43917
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.940