DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1673 and BAT1

DIOPT Version :9

Sequence 1:	NP_572884.1	Gene:	CG1673 / 32297	FlyBaseID:	FBgn0030482	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_012078.3	Gene:	BAT1 / 856615	SGDID:	S000001251	Length:	393	Species:	Saccharomyces cerevisiae

Alignment Length:	392	Identity:	175/392 - (44%)
Similarity:	235/392 - (59%)	Gaps:	32/392 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 HQFRASQISVRLAA---------------PEQLQPKPDNDEELGFGRLFTDHMLKIYYHKSLGGW 125
            |..:..:.|:|..|               |...:|:|  :|||.||:.||||||.|.: .:..||
Yeast     5 HSLKLGKFSIRTLATGAPLDASKLKITRNPNPSKPRP--NEELVFGQTFTDHMLTIPW-SAKEGW 66

  Fly   126 QRPEITPLENLVMHPAAKVLHYAVELFEGMKAYRGVDGKIRIFRPDMNMNRMNLAAQRSGLPTFE 190
            ..|.|.|..||.:.|:|.|.|||.|||||:||||.....|.:||||.||.|||.:|.|..|||||
Yeast    67 GTPHIKPYGNLSLDPSACVFHYAFELFEGLKAYRTPQNTITMFRPDKNMARMNKSAARICLPTFE 131

  Fly   191 GKEFVQCLSRLLSIDSEWVPHTDTASLYIRPTLIGIDPTLGVASSDSALLYTILSPVGSYFKTGS 255
            .:|.::...:|:..|...||..:..|||||||:||....|||.:...||||.|.||||.|:|||.
Yeast   132 SEELIKLTGKLIEQDKHLVPQGNGYSLYIRPTMIGTSKGLGVGTPSEALLYVITSPVGPYYKTGF 196

  Fly   256 SGAVSLLADPSYVRAWPGGVGNRKMGSNYAPTINVQKEAAAKGLQQVLWLYGEDHQLTEVGTMNI 320
            . ||.|.|.....||||||||::|:|:||||.|..|.:||.:|.||.|||:|.:..:|||||||:
Yeast   197 K-AVRLEATDYATRAWPGGVGDKKLGANYAPCILPQLQAAKRGYQQNLWLFGPEKNITEVGTMNV 260

  Fly   321 FMFFVND-QGEQELVTPPLSGLILPGITRDSILRMTR------QWGKFKVSEANITMPMVCELLN 378
            |..|:|. .|::||||.||.|.||.|:||||:|.:.|      :|   .::|...|:..|.....
Yeast   261 FFVFLNKVTGKKELVTAPLDGTILEGVTRDSVLTLARDKLDPQEW---DINERYYTITEVATRAK 322

  Fly   379 QGRLLELFGAGTACVVSPVNRISYLGQDLYIPTM--EQEKPVHELIRETLTDIQYGRVDH-PWAV 440
            ||.|||.||:|||.||||:..|.:..:|:::|.:  ||...:.:.:.:.:.|||||||:: .|:.
Yeast   323 QGELLEAFGSGTAAVVSPIKEIGWNNEDIHVPLLPGEQCGALTKQVAQWIADIQYGRVNYGNWSK 387

  Fly   441 VI 442
            .:
Yeast   388 TV 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1673	NP_572884.1	PRK13357	82..443	CDD:237363	174/386 (45%)
CG1673	NP_572884.1	BCAT_beta_family	138..432	CDD:238798	144/302 (48%)
BAT1	NP_012078.3	BCAT_beta_family	78..378	CDD:238798	144/303 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346297
Domainoid	1	1.000	245	1.000	Domainoid score	I361
eggNOG	1	0.900	-	-		E1_COG0115
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	315	1.000	Inparanoid score	I465
Isobase	1	0.950	-	0	Normalized mean entropy	S737
OMA	1	1.010	-	-		QHG53536
OrthoFinder	1	1.000	-	-		FOG0000948
OrthoInspector	1	1.000	-	-		otm46905
orthoMCL	1	0.900	-	-		OOG6_100313
Panther	1	1.100	-	-	LDO	PTHR11825
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R129
SonicParanoid	1	1.000	-	-		X560
TreeFam	1	0.960	-	-
	15	14.740