DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1673 and BAT2

DIOPT Version :9

Sequence 1:	NP_572884.1	Gene:	CG1673 / 32297	FlyBaseID:	FBgn0030482	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_012682.1	Gene:	BAT2 / 853613	SGDID:	S000003909	Length:	376	Species:	Saccharomyces cerevisiae

Alignment Length:	370	Identity:	175/370 - (47%)
Similarity:	235/370 - (63%)	Gaps:	12/370 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 ASQISVRLAAPEQLQPKPDNDEELGFGRLFTDHMLKIYYHKSLGGWQRPEITPLENLVMHPAAKV 144
            ||::.:   ...|...||..:.||.||:.||||||...: .:..||..|||.|.:||.:.|:|.|
Yeast     8 ASKVKI---TTTQHASKPKPNSELVFGKSFTDHMLTAEW-TAEKGWGTPEIKPYQNLSLDPSAVV 68

  Fly   145 LHYAVELFEGMKAYRGVDGKIRIFRPDMNMNRMNLAAQRSGLPTFEGKEFVQCLSRLLSIDSEWV 209
            .|||.||||||||||.||.||.:|||||||.|||.:|||..||||:.:|.:..:.:|:..|...|
Yeast    69 FHYAFELFEGMKAYRTVDNKITMFRPDMNMKRMNKSAQRICLPTFDPEELITLIGKLIQQDKCLV 133

  Fly   210 PHTDTASLYIRPTLIGIDPTLGVASSDSALLYTILSPVGSYFKTGSSGAVSLLADPSYVRAWPGG 274
            |.....||||||||||....|||::.|.||||.|..|||.|:|||.. ||.|.|.....||||||
Yeast   134 PEGKGYSLYIRPTLIGTTAGLGVSTPDRALLYVICCPVGPYYKTGFK-AVRLEATDYATRAWPGG 197

  Fly   275 VGNRKMGSNYAPTINVQKEAAAKGLQQVLWLYGEDHQLTEVGTMNIFMFFVNDQ-GEQELVTPPL 338
            .|::|:|:||||.:..|.:||::|.||.|||:|.::.:|||||||.|..|.:.: |::||||.||
Yeast   198 CGDKKLGANYAPCVLPQLQAASRGYQQNLWLFGPNNNITEVGTMNAFFVFKDSKTGKKELVTAPL 262

  Fly   339 SGLILPGITRDSILRMTRQW---GKFKVSEANITMPMVCELLNQGRLLELFGAGTACVVSPVNRI 400
            .|.||.|:||||||.:.::.   .::.:||...|:..|.|....|.|||.||:|||.:|||:..|
Yeast   263 DGTILEGVTRDSILNLAKERLEPSEWTISERYFTIGEVTERSKNGELLEAFGSGTAAIVSPIKEI 327

  Fly   401 SYLGQDLYIPTM--EQEKPVHELIRETLTDIQYGRVDH-PWAVVI 442
            .:.|:.:.||.:  ||..|:.:.:.:.:..||||..:| .|:.|:
Yeast   328 GWKGEQINIPLLPGEQTGPLAKEVAQWINGIQYGETEHGNWSRVV 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1673	NP_572884.1	PRK13357	82..443	CDD:237363	173/368 (47%)
CG1673	NP_572884.1	BCAT_beta_family	138..432	CDD:238798	147/299 (49%)
BAT2	NP_012682.1	BCAT_beta_family	61..361	CDD:238798	147/300 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346296
Domainoid	1	1.000	245	1.000	Domainoid score	I361
eggNOG	1	0.900	-	-		E1_COG0115
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20320
Inparanoid	1	1.050	315	1.000	Inparanoid score	I465
Isobase	1	0.950	-	0	Normalized mean entropy	S737
OMA	1	1.010	-	-		QHG53536
OrthoFinder	1	1.000	-	-		FOG0000948
OrthoInspector	1	1.000	-	-		otm46905
orthoMCL	1	0.900	-	-		OOG6_100313
Panther	1	1.100	-	-	O	PTHR11825
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R129
SonicParanoid	1	1.000	-	-		X560
TreeFam	1	0.960	-	-
	16	15.740