Protein Alignment Bcat and BCAT1

DIOPT Version :10

• Sequence 1: NP_572884.1
• Gene: Bcat / 32297
• FlyBaseID: FBgn0030482
• Length: 443
• Species: Drosophila melanogaster
• Sequence 2: NP_001400015.1
• Gene: BCAT1 / 586
• HGNCID: 976
• Length: 415
• Species: Homo sapiens
• Alignment Length: 362
• Identity: 188/362 - (51%)
• Similarity: 253/362 - (69%)
• Gaps: 8/362 - (2%)

  Fly    78 FRASQISVRLAAPEQLQPKPDNDEELGFGRLFTDHMLKIYYHKSLGGWQRPEITPLENLVMHPAA 142
            |:|..:.|..|...:.:|.|:|   |.||.:||||||.:.:.... ||::|.|.||:||.:||.:
Human    37 FKAKDLIVTPATILKEKPDPNN---LVFGTVFTDHMLTVEWSSEF-GWEKPHIKPLQNLSLHPGS 97

  Fly   143 KVLHYAVELFEGMKAYRGVDGKIRIFRPDMNMNRMNLAAQRSGLPTFEGKEFVQCLSRLLSIDSE 207
            ..||||||||||:||:||||.|||:|:|::||:||..:|.|:.||.|:.:|.::|:.:|:.:|.|
Human    98 SALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQE 162

  Fly   208 WVPHTDTASLYIRPTLIGIDPTLGVASSDSALLYTILSPVGSYFKTGSSGAVSLLADPSYVRAWP 272
            |||::.:||||||||.||.:|:|||.....|||:.:|||||.||.:|:...|||.|:|.|||||.
Human   163 WVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWK 227

  Fly   273 GGVGNRKMGSNYAPTINVQKEAAAKGLQQVLWLYGEDHQLTEVGTMNIFMFFVNDQGEQELVTPP 337
            ||.|:.|||.||..::..|.||...|.||||||||||||:|||||||:|::::|:.||:||.|||
Human   228 GGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPP 292

  Fly   338 LSGLILPGITRDSILRMTRQWGKFKVSEANITMPMVCELLNQGRLLELFGAGTACVVSPVNRISY 402
            |.|:||||:||..||.:..|||:|||||..:||..:...|...|:.|:||:||||||.||:.|.|
Human   293 LDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILY 357

  Fly   403 LGQDLYIPTMEQEKPVHELIRETLTDIQYGRVDHPWA 439
            .|:.::|||||....:...|...|||||    ...||
Human   358 KGETIHIPTMENGPKLASRILSKLTDIQ----SSTWA 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bcat	NP_572884.1	BCAT_beta_family	138..432	CDD:238798	162/293 (55%)
BCAT1	NP_001400015.1	PRK13357	44..385	CDD:237363	182/344 (53%)