DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1673 and bcat1

DIOPT Version :9

Sequence 1:	NP_572884.1	Gene:	CG1673 / 32297	FlyBaseID:	FBgn0030482	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_956358.1	Gene:	bcat1 / 337412	ZFINID:	ZDB-GENE-030131-9358	Length:	385	Species:	Danio rerio

Alignment Length:	389	Identity:	208/389 - (53%)
Similarity:	270/389 - (69%)	Gaps:	13/389 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 AQYTSAPEPIKHDKN----LGHQFRASQISVRLAAPEQLQPKPDNDEELGFGRLFTDHMLKIYYH 119
            |..||||.  .|.:|    ....|:|:...::||  :..:|||| ...|.||.:||||||.|.:
Zfish     5 ASATSAPS--SHKENGMADSASSFKAADTVIQLA--QTHKPKPD-PNGLVFGSVFTDHMLTIKW- 63

  Fly   120 KSL-GGWQRPEITPLENLVMHPAAKVLHYAVELFEGMKAYRGVDGKIRIFRPDMNMNRMNLAAQR 183
             || .|||:|.|.|..||.|||....||||::||||||||||.|.|:|:|||.:||.||..:|.|
Zfish    64 -SLQEGWQKPHIQPFGNLSMHPGCSALHYAIQLFEGMKAYRGPDNKVRLFRPMLNMKRMLKSAHR 127

  Fly   184 SGLPTFEGKEFVQCLSRLLSIDSEWVPHTDTASLYIRPTLIGIDPTLGVASSDSALLYTILSPVG 248
            :.||:|:..|.::|:.:|:.:|.:||||:|:|||||||||:|.:|||||....||||:.||||||
Zfish   128 ACLPSFDCAELMECIKKLVDLDQDWVPHSDSASLYIRPTLLGTEPTLGVKKPSSALLFVILSPVG 192

  Fly   249 SYFKTGSSGAVSLLADPSYVRAWPGGVGNRKMGSNYAPTINVQKEAAAKGLQQVLWLYGEDHQLT 313
            |||.||:. .|||.||..|:|||.||.|:.|||.||..:|..|.||...|.||||||||:|||:|
Zfish   193 SYFSTGAK-PVSLWADSKYIRAWRGGTGDCKMGGNYGSSIYAQYEAVDFGCQQVLWLYGDDHQIT 256

  Fly   314 EVGTMNIFMFFVNDQGEQELVTPPLSGLILPGITRDSILRMTRQWGKFKVSEANITMPMVCELLN 378
            ||||||:|::::|::||:||.||||.|:||||:||.|||.:.|||..|||||..:||..:...|.
Zfish   257 EVGTMNLFLYWINEKGEEELATPPLDGIILPGVTRQSILELARQWSGFKVSERYLTMSDLRRALE 321

  Fly   379 QGRLLELFGAGTACVVSPVNRISYLGQDLYIPTMEQEKPVHELIRETLTDIQYGRVDHPWAVVI 442
            :.|:.|:||:|||||||||.||.|.|::|:||......|:...:.:.||||||||....|:.:|
Zfish   322 ENRVKEMFGSGTACVVSPVGRILYQGENLHIPCEGSFPPLASRLLKELTDIQYGRTPSDWSCII 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1673	NP_572884.1	PRK13357	82..443	CDD:237363	199/362 (55%)
CG1673	NP_572884.1	BCAT_beta_family	138..432	CDD:238798	168/293 (57%)
bcat1	NP_956358.1	PRK13357	36..378	CDD:237363	196/347 (56%)
bcat1	NP_956358.1	BCAT_beta_family	81..375	CDD:238798	168/294 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595383
Domainoid	1	1.000	320	1.000	Domainoid score	I1214
eggNOG	1	0.900	-	-		E1_COG0115
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20320
Inparanoid	1	1.050	411	1.000	Inparanoid score	I1833
OMA	1	1.010	-	-		QHG53536
OrthoDB	1	1.010	-	-		D280685at33208
OrthoFinder	1	1.000	-	-		FOG0000948
OrthoInspector	1	1.000	-	-		otm26084
orthoMCL	1	0.900	-	-		OOG6_100313
Panther	1	1.100	-	-	LDO	PTHR11825
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R129
SonicParanoid	1	1.000	-	-		X560
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800