DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1673 and Bcat1

DIOPT Version :9

Sequence 1:	NP_572884.1	Gene:	CG1673 / 32297	FlyBaseID:	FBgn0030482	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	XP_008761592.1	Gene:	Bcat1 / 29592	RGDID:	2195	Length:	428	Species:	Rattus norvegicus

Alignment Length:	428	Identity:	208/428 - (48%)
Similarity:	279/428 - (65%)	Gaps:	29/428 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 NQSLKAAQAAQLQQKS--------------SADFEITASLDAQYTSAPEPIKHDKNLGHQ----- 77
            :|.::....|:.|::|              ||.:.....|:|...|      :|:..|.:
  Rat     8 SQRMQGLGDARSQRRSPLGNSGMEDCSNGCSASYAEEEELEASTES------YDEEGGSEASTQT 66

  Fly    78 FRASQISVRLAAPEQLQPKPDNDEELGFGRLFTDHMLKIYYHKSLGGWQRPEITPLENLVMHPAA 142
            |||..:.:..|  :.|:.||| ...|.||..||||||.:.: .|..||.:|.|.|.|||.:||||
  Rat    67 FRAKDLIITKA--DVLKKKPD-PSSLVFGASFTDHMLMVEW-TSKYGWDKPHIKPFENLSIHPAA 127

  Fly   143 KVLHYAVELFEGMKAYRGVDGKIRIFRPDMNMNRMNLAAQRSGLPTFEGKEFVQCLSRLLSIDSE 207
            .|||||||||||:||:||||.|||:||||:||.||..:|.|:.||.|:.:|.:||:.:|:.:|.|
  Rat   128 SVLHYAVELFEGLKAFRGVDNKIRLFRPDLNMKRMCRSAVRTTLPEFDKEELLQCVLQLIQLDRE 192

  Fly   208 WVPHTDTASLYIRPTLIGIDPTLGVASSDSALLYTILSPVGSYFKTGSSGAVSLLADPSYVRAWP 272
            |||::.:||||||||.|||:|:|||.....|||:.|||||||||..|:...|||.|:|.:||:|.
  Rat   193 WVPYSTSASLYIRPTFIGIEPSLGVKKPSKALLFVILSPVGSYFSNGTFSPVSLWANPKFVRSWK 257

  Fly   273 GGVGNRKMGSNYAPTINVQKEAAAKGLQQVLWLYGEDHQLTEVGTMNIFMFFVNDQGEQELVTPP 337
            ||.|:.|||.||..::..|.|||..|..|||||||:::::|||||||:|::::|..||:||.|||
  Rat   258 GGTGDFKMGCNYGSSLLAQCEAAENGCHQVLWLYGKENRITEVGTMNLFLYWINKDGEEELATPP 322

  Fly   338 LSGLILPGITRDSILRMTRQWGKFKVSEANITMPMVCELLNQGRLLELFGAGTACVVSPVNRISY 402
            |.|:||||:||.|||.:..:||:|||.|.:|||..:...|.:.|:.|:||:||||||.||..|.|
  Rat   323 LDGVILPGVTRQSILELGEEWGEFKVCERHITMDDLSTALEENRVKEMFGSGTACVVCPVASILY 387

  Fly   403 LGQDLYIPTMEQEKPVHELIRETLTDIQYGRVDHPWAV 440
            .||.|:|||||....:...|...||||||||:...|.:
  Rat   388 KGQMLHIPTMENGHKLSSRIMAKLTDIQYGRIKSEWTL 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1673	NP_572884.1	PRK13357	82..443	CDD:237363	194/359 (54%)
CG1673	NP_572884.1	BCAT_beta_family	138..432	CDD:238798	167/293 (57%)
Bcat1	XP_008761592.1	PRK13357	81..420	CDD:237363	191/340 (56%)
Bcat1	XP_008761592.1	BCAT_beta_family	122..417	CDD:238798	167/294 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353284
Domainoid	1	1.000	302	1.000	Domainoid score	I1355
eggNOG	1	0.900	-	-		E1_COG0115
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20320
Inparanoid	1	1.050	398	1.000	Inparanoid score	I1882
OMA	1	1.010	-	-		QHG53536
OrthoDB	1	1.010	-	-		D280685at33208
OrthoFinder	1	1.000	-	-		FOG0000948
OrthoInspector	1	1.000	-	-		otm45976
orthoMCL	1	0.900	-	-		OOG6_100313
Panther	1	1.100	-	-	LDO	PTHR11825
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X560
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770