DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1673 and eca39

DIOPT Version :9

Sequence 1:	NP_572884.1	Gene:	CG1673 / 32297	FlyBaseID:	FBgn0030482	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_595180.2	Gene:	eca39 / 2540831	PomBaseID:	SPBC428.02c	Length:	427	Species:	Schizosaccharomyces pombe

Alignment Length:	444	Identity:	183/444 - (41%)
Similarity:	256/444 - (57%)	Gaps:	42/444 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 INAKDI-FRNQHRLIRFLEQSIRLCSNQSLKAAQAAQLQQKSSADFEITASLDAQYTSAPEPIKH 70
            |..::| |..|...:.:.:||...|.| .|...|...:.|        ||:|     ..|:|:
pombe    12 IKGRNIRFALQRGSVGYSQQSSEACKN-FLNTTQLRTMVQ--------TAAL-----HGPKPM-- 60

  Fly    71 DKNLGHQFRASQISVRLAAPEQLQPKPDNDEELGFGRLFTDHMLKIYYHKSLGGWQRPEITPLEN 135
              :..|        :::...::|:|.|: .:.|.||..||||||.:.:::. .||..|||.|...
pombe    61 --DSSH--------IKVTNVKELKPLPE-WKSLKFGENFTDHMLIMKWNRE-KGWSTPEIVPFGK 113

  Fly   136 LVMHPAAKVLHYAVELFEGMKAYRGVDGKIRIFRPDMNMNRMNLAAQRSGLPTFEGKEFVQCLSR 200
            |..|||:.|.||..|.||||||:|...|..|:|||..|..||.....|..||:|:..|..:.:.:
pombe   114 LCFHPASSVFHYGFECFEGMKAFRDEKGVPRLFRPIKNAERMLSTGTRISLPSFDPAELAEIIRK 178

  Fly   201 LLSIDSEWVPHTDTASLYIRPTLIGIDPTLGVASSDSALLYTILSPVGSYFKTGSSGAVSLLADP 265
            .::.::.|||.....|||||||.||.|..|||...|:|:||.|.||||.|:.:|.. ||.|....
pombe   179 FVAHENRWVPDQRGYSLYIRPTFIGTDEALGVHHCDNAMLYVIASPVGPYYSSGFK-AVKLCCSE 242

  Fly   266 SYVRAWPGGVGNRKMGSNYAPTINVQKEAAAKGLQQVLWLYGEDHQLTEVGTMNIFMFFVNDQGE 330
            ..|||||||.|:.|:|.||||::..|||||.||..|:|||||::..:|||||||.|..::|..||
pombe   243 ESVRAWPGGTGHYKLGGNYAPSVLPQKEAAKKGYAQILWLYGDEDYITEVGTMNCFTVWINKNGE 307

  Fly   331 QELVTPPLSGLILPGITRDSILRMTRQ------WGKFKVSEANITMPMVCELLNQGRLLELFGAG 389
            :|::|.||.|:||||:||||||.:.|:      |   |::|...:|..|.:...:|||||:||||
pombe   308 KEIITAPLDGMILPGVTRDSILEICRERLAPKGW---KITEGKYSMKEVAQASKEGRLLEVFGAG 369

  Fly   390 TACVVSPVNRISYLGQDLYIPTMEQEK--PVHELIRETLTDIQYGR-VDHPWAV 440
            ||.:||||..|:|.|.:..||..|.::  |:...|.:.:.|||||: .::||:|
pombe   370 TAALVSPVKAINYKGTEYEIPMPEGQEAGPITSEISKWILDIQYGKEPNNPWSV 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1673	NP_572884.1	PRK13357	82..443	CDD:237363	166/368 (45%)
CG1673	NP_572884.1	BCAT_beta_family	138..432	CDD:238798	142/301 (47%)
eca39	NP_595180.2	PRK13357	64..417	CDD:237363	164/366 (45%)
eca39	NP_595180.2	BCAT_beta_family	117..414	CDD:238798	142/300 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	243	1.000	Domainoid score	I441
eggNOG	1	0.900	-	-		E1_COG0115
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	313	1.000	Inparanoid score	I568
OMA	1	1.010	-	-		QHG53536
OrthoFinder	1	1.000	-	-		FOG0000948
OrthoInspector	1	1.000	-	-		oto101758
orthoMCL	1	0.900	-	-		OOG6_100313
Panther	1	1.100	-	-	LDO	PTHR11825
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R129
SonicParanoid	1	1.000	-	-		X560
TreeFam	1	0.960	-	-
	13	12.860