DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1673 and bcat-1

DIOPT Version :9

Sequence 1:	NP_572884.1	Gene:	CG1673 / 32297	FlyBaseID:	FBgn0030482	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_510144.1	Gene:	bcat-1 / 181423	WormBaseID:	WBGene00001149	Length:	415	Species:	Caenorhabditis elegans

Alignment Length:	423	Identity:	204/423 - (48%)
Similarity:	275/423 - (65%)	Gaps:	28/423 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LIRFLEQSIRLCSNQSLKAAQAAQLQQKSSADFEITASLDAQYTSAPEPIKHDKNLGHQFRASQI 83
            |.|...::..|..::.:  |.||:|:                 |...|.|..:.:....|....:
Worm     5 LSRVAPRTFNLVGSRLM--ASAARLE-----------------TVPREEIHKEYDRKKTFYHRDL 50

  Fly    84 SVRLAAPEQLQPKPDNDEELGFGRLFTDHMLKIYYHKSLGGWQRPEITPLENLVMHPAAKVLHYA 148
            .::||.|.||:.||.:..:|.||..:.|:|:...:... .||..|:|.|:..|.:||.|||||||
Worm    51 EIQLAGPTQLKTKPLDPTKLKFGHTYADYMMTCDWDAE-RGWHHPKIEPIGELKIHPGAKVLHYA 114

  Fly   149 VELFEGMKAYRGVDGKIRIFRPDMNMNRMNLAAQRSGLPTFEGKEFVQCLSRLLSIDSEWVPHTD 213
            .|||||||||||:|.|||:|||:|||.||...|.|:.||.|:.:|.:..|:.||.:|.||||::|
Worm   115 SELFEGMKAYRGIDNKIRMFRPEMNMARMKRTALRAALPDFDSEEMINVLTELLRLDQEWVPNSD 179

  Fly   214 TASLYIRPTLIGIDPTLGVASSDSALLYTILSPVGSYFKTGSSGAVSLLADPSYVRAWPGGVGNR 278
            ..|||:||||||.||||||..:..|.::.|..|||:|:.||.. .||||||..::||:|||||..
Worm   180 VCSLYLRPTLIGTDPTLGVGCATEAKMFVITGPVGAYYSTGFQ-PVSLLADSRFIRAFPGGVGAY 243

  Fly   279 KMGSNYAPTINVQKEAAAKGLQQVLWLYGEDHQLTEVGTMNIFMFFVNDQGEQELVTPPL-SGLI 342
            |||.||||||.|.||||:|..|||||||||:..||||||||||:|:.|::|:.||:|||| .|||
Worm   244 KMGCNYAPTIWVGKEAASKNCQQVLWLYGENEDLTEVGTMNIFLFWKNEEGDMELITPPLHRGLI 308

  Fly   343 LPGITRDSILRMTRQWGKFKVSEANITMPMVCELLNQGRLLELFGAGTACVVSPVNRISYLG--- 404
            |||:||||:|.:.|:||::||:|..:.|..|.:.|::.||.|:||:|||||||||.:|.|..
Worm   309 LPGVTRDSLLELGREWGEYKVTERTLNMEEVKKALSEKRLYEMFGSGTACVVSPVGKILYHNKVT 373

  Fly   405 ---QDLYIPTMEQEKPVHELIRETLTDIQYGRV 434
               ::|:||||..:..|.:....|:.||||||:
Worm   374 DEYEELHIPTMSSKFGVMQKFYNTINDIQYGRI 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1673	NP_572884.1	PRK13357	82..443	CDD:237363	193/360 (54%)
CG1673	NP_572884.1	BCAT_beta_family	138..432	CDD:238798	172/300 (57%)
bcat-1	NP_510144.1	PRK13357	57..415	CDD:237363	191/352 (54%)
bcat-1	NP_510144.1	BCAT_beta_family	103..404	CDD:238798	172/301 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166847
Domainoid	1	1.000	311	1.000	Domainoid score	I720
eggNOG	1	0.900	-	-		E1_COG0115
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20320
Inparanoid	1	1.050	387	1.000	Inparanoid score	I1154
Isobase	1	0.950	-	0	Normalized mean entropy	S737
OMA	1	1.010	-	-		QHG53536
OrthoDB	1	1.010	-	-		D280685at33208
OrthoFinder	1	1.000	-	-		FOG0000948
OrthoInspector	1	1.000	-	-		oto18511
orthoMCL	1	0.900	-	-		OOG6_100313
Panther	1	1.100	-	-	LDO	PTHR11825
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R129
SonicParanoid	1	1.000	-	-		X560
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750