DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1662 and SYM1

DIOPT Version :9

Sequence 1:	NP_001285209.1	Gene:	CG1662 / 32296	FlyBaseID:	FBgn0030481	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_013352.1	Gene:	SYM1 / 850953	SGDID:	S000004241	Length:	197	Species:	Saccharomyces cerevisiae

Alignment Length:	178	Identity:	45/178 - (25%)
Similarity:	83/178 - (46%)	Gaps:	16/178 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 TNVGISLTLSCVGDVLEQHLEIYCGEIERFESTRTAHMAISGVTV-GVICHYWYKMLDKRM---- 137
            ||..::..|..:|||..|.|.......:.::..|||...|.|..: ..|...|||:|:.::
Yeast    18 TNAIMTGALFGIGDVSAQLLFPTSKVNKGYDYKRTARAVIYGSLIFSFIGDKWYKILNNKIYMRN 82

  Fly   138 -PGRTMRVVAKKIVLDQLICSPIYISAFFVTLGLLEQKTKHEVWEEIKEKAWKLYAAEWTVWPVA 201
             |......:..::.:|||..:|:.:..:|..:.::|.::......:|||:.|......|.|||:.
Yeast    83 RPQYHWSNMVLRVAVDQLAFAPLGLPFYFTCMSIMEGRSFDVAKLKIKEQWWPTLLTNWAVWPLF 147

  Fly   202 QFVNFYWIPTHYRIFYDNIISLGYDVL----TSKVKHKQSHSHLKKIP 245
            |.:||..:|..:|:...|::::.::..    .|||..|.      |:|
Yeast   148 QAINFSVVPLQHRLLAVNVVAIFWNTYLSYKNSKVMEKD------KVP 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1662	NP_001285209.1	Mpv17_PMP22	170..234	CDD:282035	18/67 (27%)
SYM1	NP_013352.1	Mpv17_PMP22	115..176	CDD:397992	15/60 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1944
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100380
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3951
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.700