Protein Alignment CG1640 and GPT2

DIOPT Version :10

• Sequence 1: NP_727696.2
• Gene: CG1640 / 32292
• FlyBaseID: FBgn0030478
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: XP_047290768.1
• Gene: GPT2 / 84706
• HGNCID: 18062
• Length: 554
• Species: Homo sapiens
• Alignment Length: 551
• Identity: 271/551 - (49%)
• Similarity: 365/551 - (66%)
• Gaps: 51/551 - (9%)

  Fly    56 KSTATATVTAAATSQRHGTSGDFIQPLDVRRSFSTSHKMPSSSKALTLDNINPNFIAMEYAVRGP 120
            :|.::|...|:|..:        ::|...||           .:.|||:::||...|:|||||||
Human    22 RSQSSAAAEASAVLK--------VRPERSRR-----------ERILTLESMNPQVKAVEYAVRGP 67

  Fly   121 LVIRAGEIEKELEKGVKKPFDQVIRANIGDCHAMGQQPLTFLRQLLALTFETRLLDSPDYPEDVK 185
            :|::|||||.||::|:||||.:||||||||..||||||:|||||::||.....|||||.:|||.|
Human    68 IVLKAGEIELELQRGIKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPNLLDSPSFPEDAK 132

  Fly   186 KRACAILNGCQGQS-------------------------------VGSYTDSAGLEVVRRQVAQY 219
            |||..||..|.|.|                               :|||:.|.|:..:|..||.|
Human   133 KRARRILQACGGNSLGEAPTCQAPRREMNECSQAAPASSGGSCMRMGSYSASQGVNCIREDVAAY 197

  Fly   220 IEKRDGGIASNWQDIYLTGGASPGIKSILSMINAEVGCKAPGVMVPIPQYPLYSATISEYGMTKV 284
            |.:||||:.::..:||||.|||.||.:||.::.:..|....|||:||||||||||.|||....:|
Human   198 ITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQV 262

  Fly   285 DYYLEEETGWSLDRKELQRSYDEAKKVCNPRALVVINPGNPTGQVLTRENIEEIIKFAHDNKVLV 349
            :|||:||..|:|:..||:|:..|||..|:|:.|.:||||||||||.:|:.||::|.||.:.|:.:
Human   263 NYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFL 327

  Fly   350 LADEVYQDNVYDKNSKFWSFKKVAYEMGDPY-RNLEMVSFLSTSKGYLGECGIRGGYMEVLNLDP 413
            |||||||||||..:.:|.|||||.||||..| .|:|:.||.||||||:||||.|||||||:||.|
Human   328 LADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHP 392

  Fly   414 KVKAMLTKSITAALCSTTAGQVAVSALVNPPQPGEPSYDLYKKERDGILAALKERAELVHKALNS 478
            ::|..|.|.::..||...:||.|:..:||||..||.|::.:.:|::.:|..|.::|:|.....|.
Human   393 EIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQ 457

  Fly   479 FEGYKVNPVQGAMYVFPQIEIPPKAIEAAKAKGMAPDVFYAFELLETSGICIVPGSGFGQKPGTW 543
            ..|...||:|||||.||:|.||.||:|||:|..||||:||..:|||.:|||:||||||||:.||:
Human   458 VPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTY 522

  Fly   544 HFRSTILPQTDKLKLMMEKFRVFHAEFMKKY 574
            |||.||||..:|||.:::|.:.||..|::||
Human   523 HFRMTILPPVEKLKTVLQKVKDFHINFLEKY 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1640	NP_727696.2	PTZ00377	99..575	CDD:240391	264/508 (52%)
GPT2	XP_047290768.1	PTZ00377	48..554	CDD:240391	264/506 (52%)