DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1640 and AlaAT1

DIOPT Version :9

Sequence 1:	NP_727696.2	Gene:	CG1640 / 32292	FlyBaseID:	FBgn0030478	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_173173.3	Gene:	AlaAT1 / 838301	AraportID:	AT1G17290	Length:	543	Species:	Arabidopsis thaliana

Alignment Length:	574	Identity:	243/574 - (42%)
Similarity:	350/574 - (60%)	Gaps:	38/574 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 MSRMLIKPAAATVSAALQQHQRQQQQYVIRRWKSFLHNNSNNANRRAAKSTATATVTAAATSQRH 72
            |.|.:|..|    ...:.|.:|:|           ||::.|    .:..|........:.:|.||
plant     1 MRRFVIGQA----KNLIDQSRRRQ-----------LHHHKN----LSFVSLIPPFSAPSDSSSRH 46

  Fly    73 GTSGDFIQPLDVRRSFSTSHKMPSSSKALTLDNINPNFIAMEYAVRGPLVIRAGEIEKELEKGVK 137
            .:|..         |...|....|||..:|||.|||..|..||||||.:|..|.:::::|:....
plant    47 LSSSS---------SSDMSASDSSSSLPVTLDTINPKVIKCEYAVRGEIVNIAQKLQEDLKTNKD 102

  Fly   138 K-PFDQVIRANIGDCHAMGQQPLTFLRQLLALTFETRLLDSPD----YPEDVKKRACAILNGCQG 197
            . |||::|..|||:..::||||:||.|::|||...|.|||...    :..|..:||..||:...|
plant   103 AYPFDEIIYCNIGNPQSLGQQPITFFREVLALCSYTALLDESATHGLFSSDSIERAWKILDQIPG 167

  Fly   198 QSVGSYTDSAGLEVVRRQVAQYIEKRDGGIASNWQDIYLTGGASPGIKSILSMINAEVGCKAPGV 262
            ::.|:|:.|.|::.:|..:|..||.|| |..::..||::|.|||||:..::.::   :..:..|:
plant   168 RATGAYSHSQGIKGLRDAIADGIEARD-GFPADPNDIFMTDGASPGVHMMMQLL---ITSEKDGI 228

  Fly   263 MVPIPQYPLYSATISEYGMTKVDYYLEEETGWSLDRKELQRSYDEAK-KVCNPRALVVINPGNPT 326
            :.||||||||||:|:.:|.|.|.|||:|.:||.|:..||::..::|: |....|||.||||||||
plant   229 LCPIPQYPLYSASIALHGGTLVPYYLDEASGWGLEISELKKQLEDARSKGITVRALAVINPGNPT 293

  Fly   327 GQVLTRENIEEIIKFAHDNKVLVLADEVYQDNVYDKNSKFWSFKKVAYEMGDPYRNLEMVSFLST 391
            ||||:.||..:::||.....:::|||||||:|||..:.||.||||||..||...::|.:|||.|.
plant   294 GQVLSEENQRDVVKFCKQEGLVLLADEVYQENVYVPDKKFHSFKKVARSMGYGEKDLALVSFQSV 358

  Fly   392 SKGYLGECGIRGGYMEVLNLDPKVKAMLTKSITAALCSTTAGQVAVSALVNPPQPGEPSYDLYKK 456
            ||||.||||.|||||||......|:..:.|..:..|||..:||:..|.:::||:||:.||:.|..
plant   359 SKGYYGECGKRGGYMEVTGFTSDVREQIYKMASVNLCSNISGQILASLIMSPPKPGDDSYESYIA 423

  Fly   457 ERDGILAALKERAELVHKALNSFEGYKVNPVQGAMYVFPQIEIPPKAIEAAKAKGMAPDVFYAFE 521
            |:||||::|..||:.:.:|||..||...|..:||||:||.:.:|.|||.||:|:..|||.||...
plant   424 EKDGILSSLARRAKTLEEALNKLEGVTCNRAEGAMYLFPCLHLPQKAIAAAEAEKTAPDNFYCKR 488

  Fly   522 LLETSGICIVPGSGFGQKPGTWHFRSTILPQTDKLKLMMEKFRVFHAEFMKKYK 575
            ||:.:||.:||||||.|.|||||||.|||||.||:..::::...||..||.:::
plant   489 LLKATGIVVVPGSGFRQVPGTWHFRCTILPQEDKIPAIVDRLTAFHQSFMDEFR 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1640	NP_727696.2	PTZ00377	99..575	CDD:240391	223/481 (46%)
CG1640	NP_727696.2	AAT_like	178..564	CDD:99734	182/390 (47%)
AlaAT1	NP_173173.3	PLN02231	1..543	CDD:177876	243/574 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	347	1.000	Domainoid score	I230
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68832
Inparanoid	1	1.050	435	1.000	Inparanoid score	I413
OMA	1	1.010	-	-		QHG61488
OrthoDB	1	1.010	-	-		D477122at2759
OrthoFinder	1	1.000	-	-		FOG0001270
OrthoInspector	1	1.000	-	-		otm2669
orthoMCL	1	0.900	-	-		OOG6_100524
Panther	1	1.100	-	-	LDO	PTHR11751
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X707
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840