DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1640 and Kyat1

DIOPT Version :9

Sequence 1:	NP_727696.2	Gene:	CG1640 / 32292	FlyBaseID:	FBgn0030478	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_001013182.3	Gene:	Kyat1 / 311844	RGDID:	1306912	Length:	457	Species:	Rattus norvegicus

Alignment Length:	508	Identity:	108/508 - (21%)
Similarity:	177/508 - (34%)	Gaps:	113/508 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 RSFSTSHKMPSSSKALTLDNINPNFIAMEYAVRGPLVIRAGEIEKELEKGVKKPFDQVIRANIGD 150
            |....|..|....:|..||.|:.|           |.:..|::.||        :|.|   |:|.
  Rat    27 RCLHQSLTMTKRLQARRLDGIDQN-----------LWVEFGKLTKE--------YDVV---NLGQ 69

  Fly   151 CHAMGQQPLTFLRQLLALTFETRLLDSPDY-PEDVKKRACAILNGCQGQ-SVGSYTDSAGLEVVR 213
                                     ..||: |.|...:  |......|. .:..||.:.|...:.
  Rat    70 -------------------------GFPDFSPPDFATQ--AFQQATSGNFMLNQYTRAFGYPPLT 107

  Fly   214 RQVAQYIEKRDGGIASNWQDIYLTGGASPGIKSILSMINAEVGCKAPGVMVPIPQYPLYSATISE 278
            ..:|.:..|..|.......::.:|.||...:.:....:..|    ...|::..|.:..|......
  Rat   108 NVLASFFGKLLGQEMDPLTNVLVTVGAYGALFTAFQALVDE----GDEVIIMEPAFDCYEPMTMM 168

  Fly   279 YGMTKVDYYLE----------EETGWSLDRKELQRSYDEAKKVCNPRALVVINPGNPTGQVLTRE 333
            .|...|...|:          ....|.||..||...:....|:     ||:..|.||.|:|.:|.
  Rat   169 AGGCPVFVTLKPSPAPKGKLGASNDWQLDPAELASKFTPRTKI-----LVLNTPNNPLGKVFSRM 228

  Fly   334 NIEEIIKFAHDNKVLVLADEVYQDNVYDKNSKFWSFKKVAYEMGDPYRNLEM----VSFLSTSKG 394
            .:|.:......:.|:.::|||||..|||.:...    .:|...|...|.|.:    .||.:|
  Rat   229 ELELVANLCQQHDVVCISDEVYQWLVYDGHQHV----SIASLPGMWDRTLTIGSAGKSFSAT--- 286

  Fly   395 YLGECGIRGGYMEVLNLDPKVKAMLTKSITAALCSTTAGQVAVSALVNPPQP--GEP-SYDL--- 453
                 |.:.|:  |:..|..:|.:.|....:.....|..|.||:......|.  |:| ||.|
  Rat   287 -----GWKVGW--VMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQLP 344

  Fly   454 --YKKERDGILAALKERAELVHKALNSFEGYKVNPVQGAMYVFPQI-EIPPKAIEAAKAKGMAPD 515
              .:..||.::.:|:.            .|.|:...||:.::...| :...|..:...|:....|
  Rat   345 QAMELNRDHMIRSLQS------------VGLKLWISQGSYFLIADISDFKSKMPDLPGAEDEPYD 397

  Fly   516 VFYAFELLETSGICIVPGSGFGQKPGTWHF----RSTILPQTDKLKLMMEKFR 564
            ..:|..:::..|:..:|.|.|..:|....|    |...:.....|:.|.|:.|
  Rat   398 RRFAKWMIKNMGLVGIPVSTFFSRPHQKDFDHYIRFCFVKDKATLQAMDERLR 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1640	NP_727696.2	PTZ00377	99..575	CDD:240391	105/495 (21%)
CG1640	NP_727696.2	AAT_like	178..564	CDD:99734	91/414 (22%)
Kyat1	NP_001013182.3	PRK08912	58..454	CDD:181580	98/466 (21%)
Kyat1	NP_001013182.3	AAT_like	65..451	CDD:99734	95/451 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352187
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740