DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1640 and Tat

DIOPT Version :9

Sequence 1:	NP_727696.2	Gene:	CG1640 / 32292	FlyBaseID:	FBgn0030478	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_036800.1	Gene:	Tat / 24813	RGDID:	3820	Length:	454	Species:	Rattus norvegicus

Alignment Length:	499	Identity:	122/499 - (24%)
Similarity:	196/499 - (39%)	Gaps:	131/499 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 DVRRSFSTSHKMPSSSKALTLDN--INPNFIAMEYAVRGPLVIRAGEIEKELEKGVKKPFDQVIR 145
            |||.| ..|:|..:..:|: :||  :.||                             |...||.
  Rat    42 DVRPS-DMSNKTFNPIRAI-VDNMKVQPN-----------------------------PNKTVIS 75

  Fly   146 ANIGDCHAMGQQPLTFLRQLLALTFETRLLDSPDYPEDVKKRACAILNGCQGQSVGSYTDSAGLE 210
            .:|||....|..|..                    ||..:....|:.:|    ....|..|.|..
  Rat    76 LSIGDPTVFGNLPTD--------------------PEVTQAMKDALDSG----KYNGYAPSIGYL 116

  Fly   211 VVRRQVAQYIEKRDGGIASNWQDIYLTGGASPGIKSILSMINAEVGCKAPG--VMVPIPQYPLYS 273
            ..|.:||.|....:..:.:  :|:.||.|.|..|:..|:::      ..||  :::|.|.:.||.
  Rat   117 SSREEVASYYHCHEAPLEA--KDVILTSGCSQAIELCLAVL------ANPGQNILIPRPGFSLYR 173

  Fly   274 ATISEYGMTKVDYYLEEETGWSLDRKELQRSYDEAKKVCNPRALVVINPGNPTGQVLTRENIEEI 338
            ......|:....|.|..|..|.:|.|:|:...|| |..|    |||.||.||.|.|.::.::::|
  Rat   174 TLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDE-KTAC----LVVNNPSNPCGSVFSKRHLQKI 233

  Fly   339 IKFAHDNKVLVLADEVYQDNVYDKNSKFWSFKKVAYE-MGDPYRNLEMVSFLSTSKGYLGECGIR 402
            :..|....|.:||||:|.|.|         |....|| :.:...|:.::|....:|.:|.. |.|
  Rat   234 LAVAERQCVPILADEIYGDMV---------FSDCKYEPLANLSTNVPILSCGGLAKRWLVP-GWR 288

  Fly   403 GGYMEVLN----LDPKVKAMLTKSITAALCSTTAGQVAVSALVNPPQPGEPSYDLYKKERDGILA 463
            .|::.:.:    ...:::..|.|.....|...|..|.|:.:::. ..|.|..:|        .|:
  Rat   289 LGWILIHDRRDIFGNEIRDGLVKLSQRILGPCTIVQGALKSILQ-RTPQEFYHD--------TLS 344

  Fly   464 ALKERAELVHKALNSFEGYKVNPVQ--GAMYV--------FPQIEIPPKAIEAAKAKGMAPDVFY 518
            .||..|:|.:.||.:..|  :.||:  ||||:        ||:.|               .||.:
  Rat   345 FLKSNADLCYGALAAIPG--LQPVRPSGAMYLMVGIEMEHFPEFE---------------NDVEF 392

  Fly   519 AFELLETSGICIVPGSGFGQKPGTWHFRSTI-LPQTDKLKLMME 561
            ...|:....:..:|.:.| :.|.  .||..| :|:.    :|:|
  Rat   393 TERLIAEQAVHCLPATCF-EYPN--FFRVVITVPEV----MMLE 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1640	NP_727696.2	PTZ00377	99..575	CDD:240391	116/483 (24%)
CG1640	NP_727696.2	AAT_like	178..564	CDD:99734	103/402 (26%)
Tat	NP_036800.1	TAT_ubiq	1..40	CDD:285008
		tyr_amTase_E	41..442	CDD:273529	122/499 (24%)
		AAT_like	74..436	CDD:99734	109/436 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810