DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG1640 and Tat

DIOPT Version :9

Sequence 1:NP_727696.2 Gene:CG1640 / 32292 FlyBaseID:FBgn0030478 Length:575 Species:Drosophila melanogaster
Sequence 2:NP_666326.1 Gene:Tat / 234724 MGIID:98487 Length:454 Species:Mus musculus


Alignment Length:442 Identity:114/442 - (25%)
Similarity:179/442 - (40%) Gaps:100/442 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   139 PFDQVIRANIGDCHAMGQQPLTFLRQLLALTFETRLLDSPDYPEDVKKRACAILNGCQGQSVGSY 203
            |...||..:|||....|..|..                    ||..:....|:.:|    ....|
Mouse    69 PNKTVISLSIGDPTVFGNLPTD--------------------PEVTQAMKDALDSG----KYNGY 109

  Fly   204 TDSAGLEVVRRQVAQYIEKRDGGIASNWQDIYLTGGASPGIKSILSMINAEVGCKAPG--VMVPI 266
            ..|.|....|.:||.|....:..:.:  :|:.||.|.|..|:..|:::      ..||  :::|.
Mouse   110 APSIGYLSSREEVASYYHCPEAPLEA--KDVILTSGCSQAIELCLAVL------ANPGQNILIPR 166

  Fly   267 PQYPLYSATISEYGMTKVDYYLEEETGWSLDRKELQRSYDEAKKVCNPRALVVINPGNPTGQVLT 331
            |.:.||.......|:....|.|..|..|.:|.|:|:...|| |..|    |||.||.||.|.|.:
Mouse   167 PGFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDE-KTAC----LVVNNPSNPCGSVFS 226

  Fly   332 RENIEEIIKFAHDNKVLVLADEVYQDNVYDKNSKFWSFKKVAYE-MGDPYRNLEMVSFLSTSKGY 395
            :.::::|:..|....|.:||||:|.|.|         |....|| |.....|:.::|....:|.:
Mouse   227 KRHLQKILAVAERQCVPILADEIYGDMV---------FSDCKYEPMATLSTNVPILSCGGLAKRW 282

  Fly   396 LGECGIRGGYMEVLN----LDPKVKAMLTKSITAALCSTTAGQVAV-SALVNPPQPGEPSYDLYK 455
            |.. |.|.|::.:.:    ...:::..|.|.....|...|..|.|: |.|...||      :.|:
Mouse   283 LVP-GWRLGWILIHDRRDIFGNEIRDGLVKLSQRILGPCTIVQGALKSILQRTPQ------EFYQ 340

  Fly   456 KERDGILAALKERAELVHKALNSFEGYKVNPVQ--GAMYV--------FPQIEIPPKAIEAAKAK 510
                ..|:.||..|:|.:.||::..|  :.||:  ||||:        ||:.|            
Mouse   341 ----DTLSFLKSNADLCYGALSAIPG--LQPVRPSGAMYLMVGIEMEHFPEFE------------ 387

  Fly   511 GMAPDVFYAFELLETSGICIVPGSGFGQKPGTWHFRSTI-LPQTDKLKLMME 561
               .||.:...|:....:..:|.:.| :.|.  .||..| :|:.    :|:|
Mouse   388 ---NDVEFTERLIAEQSVHCLPATCF-EYPN--FFRVVITVPEV----MMLE 429

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1640NP_727696.2 PTZ00377 99..575 CDD:240391 114/442 (26%)
AAT_like 178..564 CDD:99734 106/403 (26%)
TatNP_666326.1 TAT_ubiq 1..40 CDD:369474
tyr_amTase_E 41..442 CDD:273529 114/442 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0436
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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