DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1640 and gpt2

DIOPT Version :9

Sequence 1:	NP_727696.2	Gene:	CG1640 / 32292	FlyBaseID:	FBgn0030478	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	XP_002931716.2	Gene:	gpt2 / 100494152	XenbaseID:	XB-GENE-998352	Length:	538	Species:	Xenopus tropicalis

Alignment Length:	535	Identity:	288/535 - (53%)
Similarity:	372/535 - (69%)	Gaps:	24/535 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 HNNSNNANRRAA---KSTATATVTAAATSQRHGTSGDFIQPLDVRRSFSTSHKMPSSSKALTLDN 105
            |..|.|..||.|   :|...:.|.|.|.  .|..||      .|||            |.|||.:
Frog    23 HRQSRNGQRRMAVLGQSPYCSAVEAPAV--HHAVSG------RVRR------------KILTLQS 67

  Fly   106 INPNFIAMEYAVRGPLVIRAGEIEKELEKGVKKPFDQVIRANIGDCHAMGQQPLTFLRQLLALTF 170
            :||...|:|||||||:|::||||||||:.|||||||:||:|||||.|||||||:|||||::||..
Frog    68 MNPQVRAVEYAVRGPIVLKAGEIEKELQNGVKKPFDEVIKANIGDAHAMGQQPITFLRQVVALCT 132

  Fly   171 ETRLLDSPDYPEDVKKRACAILNGCQGQSVGSYTDSAGLEVVRRQVAQYIEKRDGGIASNWQDIY 235
            ...|||:|.:|:|.|:||..||..|.|||:|||:.|.|:..:|..||::|||||.|:.::..:||
Frog   133 YPDLLDNPSFPKDAKRRARRILESCSGQSLGSYSASQGVNCIREDVAKFIEKRDEGVPAHPDNIY 197

  Fly   236 LTGGASPGIKSILSMINAEVGCKAPGVMVPIPQYPLYSATISEYGMTKVDYYLEEETGWSLDRKE 300
            ||.|||.||.|||.::.:..|....|||:||||||||||.|||....:|:|||:||..|:||..|
Frog   198 LTTGASDGISSILKILVSGEGQSRTGVMIPIPQYPLYSAAISELDAIQVNYYLDEENCWALDVNE 262

  Fly   301 LQRSYDEAKKVCNPRALVVINPGNPTGQVLTRENIEEIIKFAHDNKVLVLADEVYQDNVYDKNSK 365
            |:|::..||:.|:|:.|.:||||||||||.::..|||:|.||.:..:.:|||||||||:|.|:.:
Frog   263 LRRAFYRAKEYCSPKVLCIINPGNPTGQVQSKHCIEEVIHFALEEGLFLLADEVYQDNIYSKSCQ 327

  Fly   366 FWSFKKVAYEMGDPY-RNLEMVSFLSTSKGYLGECGIRGGYMEVLNLDPKVKAMLTKSITAALCS 429
            |:|||||.|:||..| .|:|:.||.||||||:||||.|||||||:||.|.:.|.|.|.::..||.
Frog   328 FYSFKKVLYDMGPEYFNNVELASFHSTSKGYMGECGYRGGYMEVVNLHPDITAQLVKLLSVRLCP 392

  Fly   430 TTAGQVAVSALVNPPQPGEPSYDLYKKERDGILAALKERAELVHKALNSFEGYKVNPVQGAMYVF 494
            ..:||.|:..:||||||||.||:.:.:|:|.||..|.|:|||..:..|...|.|.||:|||||.|
Frog   393 PVSGQAAMDVVVNPPQPGEESYEQFIREKDAILCNLAEKAELTEELFNQVPGIKCNPLQGAMYAF 457

  Fly   495 PQIEIPPKAIEAAKAKGMAPDVFYAFELLETSGICIVPGSGFGQKPGTWHFRSTILPQTDKLKLM 559
            |:|.||.||||.||...||||::|...|||.:|||:|||||||||.||.|||.||||..:|||::
Frog   458 PRIFIPDKAIEKAKEHQMAPDMYYCMCLLEETGICVVPGSGFGQKEGTHHFRMTILPPVEKLKIL 522

  Fly   560 MEKFRVFHAEFMKKY 574
            ::|.:.||..|::.|
Frog   523 LQKVKDFHMRFLEDY 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1640	NP_727696.2	PTZ00377	99..575	CDD:240391	272/477 (57%)
CG1640	NP_727696.2	AAT_like	178..564	CDD:99734	214/386 (55%)
gpt2	XP_002931716.2	PTZ00377	59..538	CDD:240391	274/491 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	407	1.000	Domainoid score	I695
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68832
Inparanoid	1	1.050	563	1.000	Inparanoid score	I1077
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D365656at33208
OrthoFinder	1	1.000	-	-		FOG0001270
OrthoInspector	1	1.000	-	-		otm47595
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X707
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060