Protein Alignment dmrt11E and DMRTA1

DIOPT Version :10

• Sequence 1: NP_511146.2
• Gene: dmrt11E / 32291
• FlyBaseID: FBgn0030477
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_071443.2
• Gene: DMRTA1 / 63951
• HGNCID: 13826
• Length: 504
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 67/196 - (34%)
• Similarity: 93/196 - (47%)
• Gaps: 40/196 - (20%)

  Fly   118 RTPKCARCRNHGVISCVKGHKRLCRWRECCCPNCQLVVDRQRVMAAQVALRRQQTMEALEATA-S 181
            |||||||||||||:|.:|||||.||||:|.|..|.|:.:|||||||||||||||..|..||.. .
Human    93 RTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLQ 157

  Fly   182 STKSTGVTTASANNSSSSEGE-DSLSSTSPPPAHSHPHSHSHPTSCVSNSSSSSATRQALMAQKR 245
            ....:|::......:|...|. ::..||..|.|.:                       ||
Human   158 RLLCSGLSWPPGGRASGGGGRAENPQSTGGPAAGA-----------------------AL----- 194

  Fly   246 IYKQRLRSLQQSTLHITAAMEEYKQRFPTFSSPLMERMRKRRAFADPELNHVMEATLGGNALYFA 310
                .|.:|:|::...|.|.|.::|.:|.      |:..::.:..:...|...|.....:.||..
Human   195 ----GLGALRQASGSATPAFEVFQQDYPE------EKQEQKESKCESCQNGQEELISKSHQLYLG 249

  Fly   311 T 311
            :
Human   250 S 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmrt11E	NP_511146.2	DM	118..164	CDD:459924	33/45 (73%)
DMRTA1	NP_071443.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27
		DM	93..139	CDD:459924	33/45 (73%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..192		6/21 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	266..307
		CUE_DMA_DMRTA1	325..364	CDD:270600
		DMRT5_DMB	405..491	CDD:466773