DRSC/TRiP Functional Genomics Resources

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Protein Alignment dmrt11E and DMRT3

DIOPT Version :9

Sequence 1:NP_511146.2 Gene:dmrt11E / 32291 FlyBaseID:FBgn0030477 Length:377 Species:Drosophila melanogaster
Sequence 2:NP_067063.1 Gene:DMRT3 / 58524 HGNCID:13909 Length:472 Species:Homo sapiens


Alignment Length:247 Identity:81/247 - (32%)
Similarity:124/247 - (50%) Gaps:32/247 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   116 LLRTPKCARCRNHGVISCVKGHKRLCRWRECCCPNCQLVVDRQRVMAAQVALRRQQTMEALEATA 180
            |.|||||||||||||:|.:|||||.||:::|.|..|.|:::|||||||||||||||..|:||:..
Human    23 LQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLI 87

  Fly   181 SSTKSTGVTTASANNSSSSEGEDSLSSTSPPPAHSHPHSHSHPTSCVSNSSSSSATR-------- 237
            ..       :..|.......| |::::..|||| |.| |...|....:..::::|.|        
Human    88 PD-------SLRALPGPPPPG-DAVAAPQPPPA-SQP-SQPQPPRPAAELAAAAALRWTAEPQPG 142

  Fly   238 --QALMAQKRIYKQRLRSLQQSTLHITAAMEEYKQRFPTFSSPLMERMRKRRAFADPELNHVMEA 300
              ||.:|:..:.::||...:.:......:.::..||    |||   .:.|.:....||...::..
Human   143 ALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQR----SSP---DVAKSKGCFTPESPEIVSV 200

  Fly   301 TLGGNALYFATVAAAAAACAP-VHQEQ-HIYHPMPP---TIPLTIPPTNPAM 347
            ..||.|:........:...:| .|.|| |:....|.   ::|.::....|.:
Human   201 EEGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVSLPFSLKANRPPL 252

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dmrt11ENP_511146.2 DM 118..164 CDD:279137 31/45 (69%)
DMRT3NP_067063.1 DM 25..71 CDD:279137 31/45 (69%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 89..128 11/48 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 155..191 8/42 (19%)
CUE_DMA_DMRTA3 247..289 CDD:270602 1/6 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 430..472
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3815
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D383821at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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