DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dmrt11E and dmrt3a

DIOPT Version :9

Sequence 1:	NP_511146.2	Gene:	dmrt11E / 32291	FlyBaseID:	FBgn0030477	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_001005779.2	Gene:	dmrt3a / 450035	ZFINID:	ZDB-GENE-021220-3	Length:	448	Species:	Danio rerio

Alignment Length:	237	Identity:	75/237 - (31%)
Similarity:	105/237 - (44%)	Gaps:	68/237 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 ICQRERRLLRTPKCARCRNHGVISCVKGHKRLCRWRECCCPNCQLVVDRQRVMAAQVALRRQQTM 173
            :.|....|.|||||||||||||:|.:|||||.||:::|.|..|.|:::|||||||||||||||..
Zfish    15 VSQPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQAN 79

  Fly   174 EALEA--TASSTKSTGVTTASANNSSS-------------------------------SEGEDSL 205
            |:||:  ..|.....|:|.:|...|::                               |.||:.
Zfish    80 ESLESLIPESLRALPGITVSSGEQSANPRASDIDLRWNTETGTPKTPQDLSDELSGEQSGGENG- 143

  Fly   206 SSTSPPPAHSHPHSHSHPTSCVSNSSSSSATRQALMAQKRIYKQRLRSLQQSTLHITAAME--EY 268
            .|...|.|.|.| ..|.|..|.:..:|..:.:                |::|...::.:..  |.
Zfish   144 GSDREPEAVSSP-EESKPNLCCTPDTSDPSPQ----------------LEESRFGLSKSCSDPEP 191

  Fly   269 KQRFPTFSSPLMERMRKRRAFADPELNHVMEATLGGNALYFA 310
            |...|.:|               ||.|.::|...|..:|.|:
Zfish   192 KSDNPKYS---------------PEPNLLIEGLSGSVSLPFS 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dmrt11E	NP_511146.2	DM	118..164	CDD:279137	31/45 (69%)
dmrt3a	NP_001005779.2	DM	24..70	CDD:279137	31/45 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	98..203		22/137 (16%)
		CUE_DMA_DMRTA3	221..263	CDD:270602
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	424..448
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D383821at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820