DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dmrt11E and Dmrta1

DIOPT Version :9

Sequence 1:	NP_511146.2	Gene:	dmrt11E / 32291	FlyBaseID:	FBgn0030477	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_783578.1	Gene:	Dmrta1 / 242523	MGIID:	2653627	Length:	490	Species:	Mus musculus

Alignment Length:	178	Identity:	66/178 - (37%)
Similarity:	86/178 - (48%)	Gaps:	26/178 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 RTPKCARCRNHGVISCVKGHKRLCRWRECCCPNCQLVVDRQRVMAAQVALRRQQTMEALEATASS 182
            |||||||||||||:|.:|||||.||||:|.|..|.|:.:|||||||||||||||..|..||....
Mouse    82 RTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLH 146

  Fly   183 ----TKSTGVTTASANNSSSSEGEDSLSSTSP-----PPAHSHPHSHSHPTSCV----------- 227
                ..|:|....::..|..:|....|::...     ..|..||.|.|.||..|
Mouse   147 RLLYQGSSGSGAQASGGSGRTESPQVLNNPMAVAVLGAGASRHPGSRSVPTFEVFQQDYADRKQE 211

  Fly   228 --SNSSSSSATRQALMAQKRIYKQRLRSLQQSTLHITAAMEEYKQRFP 273
              ..:..|..:||    ::.:......||..|..::|...:.:....|
Mouse   212 PKQRNCESCQSRQ----EEPVSNTHHHSLGSSKGNVTVEKQGFMSSIP 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dmrt11E	NP_511146.2	DM	118..164	CDD:279137	33/45 (73%)
Dmrta1	NP_783578.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
		DM	82..128	CDD:279137	33/45 (73%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	152..171		4/18 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	207..289		8/53 (15%)
		DMA	315..350	CDD:281472
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900