Protein Alignment dmrt11E and DMRT2

DIOPT Version :9

• Sequence 1: NP_511146.2
• Gene: dmrt11E / 32291
• FlyBaseID: FBgn0030477
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_001374487.1
• Gene: DMRT2 / 10655
• HGNCID: 2935
• Length: 561
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 119/399 - (29%)
• Similarity: 159/399 - (39%)
• Gaps: 131/399 - (32%)

  Fly    22 AANGRQGTDPESDPLHAR-CVVPHASTPRGRRIPWG----HNDDDDDG---NHLTLPDSLTATSS 78
            :|.|....|.||..|... |..|. |||.|...|..    .:|:||||   :.....|...|.:|
Human     8 SAAGDWEIDVESLELEEDVCGAPR-STPPGPSPPPADGDCEDDEDDDGVDEDAEEEGDGEEAGAS 71

  Fly    79 CGC----------QCLNVRAPFHILLVDQQARMSKDASVRIC------QRERRLLRTPKCARCRN 127
            .|.          |.....||        ||..:.......|      ...|:|.||||||||||
Human    72 PGMPGQPEQRGGPQPRPPLAP--------QASPAGTGPRERCTPAGGGAEPRKLSRTPKCARCRN 128

  Fly   128 HGVISCVKGHKRLCRWRECCCPNCQLVVDRQRVMAAQVALRRQQTMEALEATASSTKSTGVTTAS 192
            |||:||:|||||.||||:|.|.||.|||:|||||||||||||||
Human   129 HGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQ--------------------- 172

  Fly   193 ANNSSSSEGEDSLSSTSPPPAHSHPHSHSHPTSCVSNSSSSSATRQALMAQKRIYKQRLRSLQQS 257
                 ::|.:..||.                             :|....:|.:|::::|:   .
Human   173 -----ATEDKKGLSG-----------------------------KQNNFERKAVYQRQVRA---P 200

  Fly   258 TLHITAAMEEYKQ---------RFPTFSSPLMERMRKRRAFADPELNHVM------EATLGGNAL 307
            :|...:.:|.|:.         .|| ...|:.:||||||||||.||.::|      |..:
Human   201 SLLAKSILEGYRPIPAETYVGGTFP-LPPPVSDRMRKRRAFADKELENIMLEREYKEREM----- 259

  Fly   308 YFATVAAAAAACAP--------VHQEQHIYHPMPPTIPLTIPPT----NPAMTTPAVTTASTGSG 360
              ...:.|||...|        .:..:..|.|.|     ..||:    |...|...:|...:|||
Human   260 --LETSQAAALFLPNRMVPGPDYNSYKSAYSPSP-----VEPPSKDFCNFLPTCLDLTMQYSGSG 317

  Fly   361 KKPKLSFSI 369
            ....:|.::
Human   318 NMELISSNV 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dmrt11E	NP_511146.2	DM	118..164	CDD:279137	37/45 (82%)
DMRT2	NP_001374487.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..119		30/119 (25%)
		DM	119..165	CDD:395608	37/45 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	414..435

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149701
Domainoid	1	1.000	95	1.000	Domainoid score	I7438
eggNOG	1	0.900	-	-		E1_KOG3815
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D383821at33208
OrthoFinder	1	1.000	-	-		FOG0007982
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10870
SonicParanoid	1	1.000	-	-		X5931
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.740