Protein Alignment Syt12 and Syt13

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_110466.3
• Gene: Syt13 / 80977
• RGDID: 621877
• Length: 426
• Species: Rattus norvegicus
• Alignment Length: 294
• Identity: 80/294 - (27%)
• Similarity: 127/294 - (43%)
• Gaps: 65/294 - (22%)

  Fly   489 LNYDQMSISNEGMELTVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTLTPSYNE 553
            |:|||     :..||.|:.|||                   :..||.|.....:.......:.:.
  Rat   166 LDYDQ-----KKAELFVTSLEA-------------------VTSDHEGGCDCYIQGSVAVKTGSV 206

  Fly   554 SFDFWLHKRQARHSLWFHLYHNGPA-------------------------HTLIGEAEMEIGEMP 593
            .....|.|||. |:.|    ..|.|                         |::|||..:.:....
  Rat   207 EAQTALKKRQL-HTTW----EEGLALPLGEEELPTATLTLTLRTCDRFSRHSVIGELRLGLNGAS 266

  Fly   594 RPITT--WIPL-SDSRKCNARWGELMFSLSYLPTAERLTIVVVKARNLKLDGEQPAPESAETV-H 654
            .|:.|  |..| :.:::.:|..||::.|:||||.|.||.:|::||:||.      :.:|.|.: .
  Rat   267 VPLGTAQWGELKTTAKEPSAGTGEVLLSISYLPAANRLLVVLIKAKNLH------SNQSKELLGK 325

  Fly   655 SVFVKVYLMDKDRKVLKKRTSLKRKDRSPIFNESMIFSVPPPSLTTTQLRVTVFGVTTSGVT-PL 718
            .|.|||.|..:.:|:.||:|...:...:|::||.::|.:|...|..:.:.:.|.|....|.: .|
  Rat   326 DVSVKVTLKHQAQKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQGEEGPSCEL 390

  Fly   719 GHIVAGSCAVGKGLRHWHQMLSSLRKPVAMWHVL 752
            |....|..|.|....||.:||.:.|:.:||||.|
  Rat   391 GRCSLGLHASGSERSHWEEMLKNPRRQIAMWHQL 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	23/125 (18%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	50/143 (35%)
Syt13	NP_110466.3	C2	160..277	CDD:472691	28/139 (20%)
		C2B_Synaptotagmin-13	288..425	CDD:176052	50/143 (35%)