Protein Alignment Syt12 and syt7

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_031756132.1
• Gene: syt7 / 780295
• XenbaseID: XB-GENE-955540
• Length: 690
• Species: Xenopus tropicalis
• Alignment Length: 847
• Identity: 190/847 - (22%)
• Similarity: 317/847 - (37%)
• Gaps: 271/847 - (31%)

  Fly     1 MMSFTITLALLLLAVLILGILFAC-HCLGPRAANWMRMRSSKEEKIGLSNHKQKLFHANGYMASI 64
            ::|..:||: |.:.:::.|:...| ..||.|..|.:....:.:...|:.:.|
 Frog    20 LVSTVLTLS-LSITIIMCGLCQWCQRKLGKRYKNSLETAGTPDSTRGIRSEK------------- 70

  Fly    65 QSGSEFLLSTSGSFKRFDTIDKEDYNRSQQT-HQ------THLFLMN-------GGGAVSITG-- 113
                          |..:.:||:.:|.:..| ||      ...|::|       |...:::.|
 Frog    71 --------------KTLNDLDKDFWNNNDSTAHQKWSSYPPKEFILNISPYAPYGDPRLALNGTV 121

  Fly   114 ---SSSALQATTAMWHLPRSG-----------IKIPPPPDRPAPSPNSAAAAGKTVTFSLSQVNE 164
               |.||...|:.:  |.:.|           :||    ...:.|.:|....||:.......|..
 Frog   122 LSSSKSAACGTSGL--LDKDGRLGDKQFRSDSMKI----SMSSQSHHSEPVLGKSGRGRWHTVQS 180

  Fly   165 VIMPGEQVTSNDQERRSCLRQNGGTAGGAGGGGVLPQPLEAPPPPRLTASTSVNLSGTAIPRPIA 229
            .:..|....:|.::                              |.|||:|:::      ..||:
 Frog   181 HLASGNLSRTNFED------------------------------PTLTAATTLD------HIPIS 209

  Fly   230 KRQVSTQPANNSGCQPEQTVVTPMREGERKAPALKRRNSSTNPFLCESTEQIPSNPISEPLNATV 294
                    |.:..||..:|              |.|:.|                 :.:||
 Frog   210 --------AGDMKCQRPRT--------------LLRQQS-----------------LQQPL---- 231

  Fly   295 ASLEKTTISTSECTPITA----PLETPNGPISTDTPSTIHHNGNPFVERESLSSRLLKIHNTTNP 355
             ||.:   ..:.|.|.|:    .|:..:.|.||.:.:|                     .||...
 Frog   232 -SLHQ---KHNHCQPTTSQSLGQLQLQHQPPSTSSSNT---------------------SNTRPQ 271

  Fly   356 FTGLSQRVKGPHLLQKTISEDYLFRKLGVNCPMANGNGTGPGS-----GHVNGNGNGTWSF--GR 413
            .||.:         :...|.....|..|:.      |.|..||     |.:...|....||  ||
 Frog   272 RTGQN---------RPPTSAGSKHRPAGIR------NRTNAGSWDYVVGQIRNRGLDMKSFLEGR 321

  Fly   414 SLLRQDSTLSLGMGLGRR-----------NSSQVSLDSH-------------AGSVPGSMDGINL 454
            .::     |||.:||..:           |.||.:.::.             |..|||.....:.
 Frog   322 MVV-----LSLVLGLSEQDDFANIPDLQTNGSQQNQNTQGDKRLQTGGKTTSASGVPGQGQSEDP 381

  Fly   455 ER------AIS--CDSVTSDSTLFLDQLDQPYTQITG--------YLCVGLNYDQMSISNEGMEL 503
            :|      ::|  .:|:||:..:.....|:.....|.        ...||.|:.:.:       |
 Frog   382 DRKTDQHASVSDLVNSLTSEMLMLSPGSDEDDGHDTSGRENLGRIQFSVGYNFQEST-------L 439

  Fly   504 TVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTLTPSYNESFDF--WLHKRQARH 566
            ||.:|:|:.|.......:.|.||:|||:||....::|||.:..|.|.:||:|.|  :.:::..:.
 Frog   440 TVKILKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQR 504

  Fly   567 SLWFHL--YHNGPAHTLIGEAEMEIG--EMPRPITTWIPLSDSRKCNARWGELMFSLSYLPTAER 627
            .|:..:  |.....:..|||..:.:.  ::.:..|.|..|......:...|||:.||.|.|:...
 Frog   505 VLYLQVLDYDRFSRNDPIGEVSIPLNKTDLTQMQTFWKELKPCSDGSGSRGELLLSLCYNPSTNA 569

  Fly   628 LTIVVVKARNLK-LD-GEQPAPESAETVHSVFVKVYLMDKDRKVLKKRTSLKRKDRSPIFNESMI 690
            :.:.::|||||| :| |....|         :|||:||.||::|.||:|.:.::..:||||||.|
 Frog   570 IIVNIIKARNLKAMDIGGTSDP---------YVKVWLMYKDKRVEKKKTVVMKRCLNPIFNESFI 625

  Fly   691 FSVPPPSLTTTQLRVTVFG---VTTSGVTPLGHIVAGSCAVGKG-LRHWHQMLSSLRKPVAMWHV 751
            |.:|...|..|.:.:||..   ::.:.|  :|.|.. |...|.| ::||..|:|..|..||.||.
 Frog   626 FDIPTEKLRETTIIITVMDKDKLSRNDV--IGKIYL-SWKSGPGEVKHWKDMISHPRTAVAQWHQ 687

  Fly   752 LR 753
            |:
 Frog   688 LK 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	30/104 (29%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	55/146 (38%)
syt7	XP_031756132.1	C2A_Synaptotagmin-7	422..546	CDD:176032	34/130 (26%)
		C2B_Synaptotagmin-7	554..689	CDD:176050	55/146 (38%)