Protein Alignment Syt12 and syt3

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001186849.1
• Gene: syt3 / 779540
• XenbaseID: XB-GENE-956378
• Length: 544
• Species: Xenopus tropicalis
• Alignment Length: 278
• Identity: 89/278 - (32%)
• Similarity: 139/278 - (50%)
• Gaps: 41/278 - (14%)

  Fly   502 ELTVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTLTPSYNESFDF-----WLHK 561
            :|.|.:|:|..|....:....|.:|::||:||.....||||.:.||.|.:||:|.|     .|..
 Frog   263 QLVVKILKALELPAKDANGFSDPYVKMYLLPDRKKKFQTKVHRKTLNPIFNETFHFNVPFNELQN 327

  Fly   562 RQARHSLW-FHLYHNGPAHTLIGEAE----MEIGEMPRPITTWIPLSDSRKCNARWGELMFSLSY 621
            |:...|:: |..:..   |.|||:..    :|..........|..:.::....|..||:.|||.|
 Frog   328 RKLHFSIYDFDRFSR---HDLIGQVVLDNLLEFSNATDETPIWRDILEASSEKADLGEINFSLCY 389

  Fly   622 LPTAERLTIVVVKARNLK---LDG-EQPAPESAETVHSVFVKVYLMDKDRKVLKKRTSLKRKDRS 682
            ||||.|||..::||.|||   |.| ..|           :||..|:.:.|::.|::||:|:...:
 Frog   390 LPTAGRLTATIIKATNLKAMDLTGFSDP-----------YVKASLICEGRRLKKRKTSIKKNTLN 443

  Fly   683 PIFNESMIFSVPPPSLTTTQLRVTVFGVTTSGVTPLGH-IVAGSCAVG-----KGLRHWHQMLSS 741
            |.:||:::|.:|..::....|.:.|.....     :|| .|.|.|.||     :|..||::||::
 Frog   444 PTYNEALVFDIPNENMDHVSLTIAVMDYDC-----IGHNEVIGMCRVGSDADMQGREHWNEMLAN 503

  Fly   742 LRKPVAMWHVL--RRAVN 757
            .|||:..||.|  .:|:|
 Frog   504 PRKPIEHWHQLVEEKALN 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	32/108 (30%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	54/152 (36%)
syt3	NP_001186849.1	C2A_Synaptotagmin-1-5-6-9-10	248..372	CDD:176031	32/111 (29%)
		C2B_Synaptotagmin-3-5-6-9-10	381..514	CDD:176048	53/148 (36%)