Protein Alignment Syt12 and Syt8

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_445777.2
• Gene: Syt8 / 60566
• RGDID: 68399
• Length: 387
• Species: Rattus norvegicus
• Alignment Length: 349
• Identity: 102/349 - (29%)
• Similarity: 162/349 - (46%)
• Gaps: 63/349 - (18%)

  Fly   426 MGLG-RRNSSQVSLDSHAGSVPGSMDGINLERAISCDSVTSDSTLFLDQLDQPYTQITGYLCVGL 489
            :||| .|||:...|               ::..:.|....|..       |||:    |.|.:.|
  Rat    75 VGLGSARNSTTTHL---------------VQPDVECLEPCSGG-------DQPW----GQLLLSL 113

  Fly   490 NYDQMSISNEGMELTVSVLEAKGLICPFSVE-SLDTFVRIYLVPDHPGAMQTKVVKGTLTPSYNE 553
            .||..|     .|:.|.:.:||.|    ..| :.|.:.|:.:........:|||.:|||.|.:.|
  Rat   114 EYDFGS-----QEIRVGLRQAKNL----KAEGTADPYARVSVSTQAGRRHETKVHRGTLCPMFEE 169

  Fly   554 SFDFWLHKRQ-ARHSLWFHL--YHNGPAHTLIGEAEMEIG--EMPRPITTWIPLSDSRKCNA-RW 612
            :..|.:...: .:.:|...|  :.....|..:||.::.:|  ::...:.:|..|.......: :.
  Rat   170 TCCFLVPPAELPKATLKVQLLDFKRFSEHEPLGELQLPLGTVDLQHVLESWYQLGPPGSTESEQM 234

  Fly   613 GELMFSLSYLPTAERLTIVVVKARNLKLDGEQPAPESAETVHSVFVKVYLMDKDRKVLKKRTSLK 677
            |||.|||.|:|::.|||:|:::||.|.       |..||    .:|||.|:...||..|.:||.|
  Rat   235 GELCFSLRYVPSSGRLTVVILEARGLN-------PGLAE----AYVKVQLILNQRKWKKNKTSSK 288

  Fly   678 RKDRSPIFNESMIFSVPPPSLTTTQLRVTVFGVTTSGV----TPLGHIVAGSCAVGKGLRHWHQM 738
            :...:|.|||:.:|.||...|.:..|   |..|...|:    .|:|.::.|..|.|:.|:||..|
  Rat   289 KGTTNPYFNEAFVFLVPVSQLQSMDL---VLAVWARGLQLLAEPVGKVLLGPRASGQPLQHWADM 350

  Fly   739 LSSLRKPVAMWHVLR--RAVNQPI 760
            |:..|:|:|.||.||  |.|::.:
  Rat   351 LAHARRPIAQWHHLRSPREVDRAL 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	23/104 (22%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	55/144 (38%)
Syt8	NP_445777.2	Syt1_2_N	<27..72	CDD:425364
		C2	107..225	CDD:472691	31/126 (25%)
		C2	234..364	CDD:472691	55/143 (38%)