Protein Alignment Syt12 and Doc2g

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_068563.2
• Gene: Doc2g / 60425
• MGIID: 1926250
• Length: 387
• Species: Mus musculus
• Alignment Length: 328
• Identity: 77/328 - (23%)
• Similarity: 121/328 - (36%)
• Gaps: 92/328 - (28%)

  Fly   483 GYLCVGLNYDQMSISNEGMELTVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQ--TKVVKG 545
            |.|...|.:|:   .|..:..|..  .||||..| :..|:||:|:..|:|....|.|  |:.|:|
Mouse    85 GTLEFTLLFDE---DNSALHCTAH--RAKGLKPP-AAGSVDTYVKANLLPGASKASQLRTRTVRG 143

  Fly   546 TLTPSYNESF---------------------DFWLHKRQARHSLWFHLYHNGPAHTLIGEAEMEI 589
            |..|.:.|:.                     |..|.:|:           .||          .:
Mouse   144 TREPVWEETLTYHGFTCQDAGRKTLRLCVCEDSRLRRRR-----------RGP----------PL 187

  Fly   590 GEMPRPITTWIP--------LSDSRKCNAR--------------------------WGELMFSLS 620
            ||:..|:...:|        ..:.||...|                          .|.::.||.
Mouse   188 GELRVPLRKLVPNRARSFDICLEKRKLTKRPKSLDTARGMSLYEEEEMEAEVFGEERGRILLSLC 252

  Fly   621 YLPTAERLTIVVVKARNLKLDGEQPAPESAETVHSVFVKVYLMDKDRKVLKKRTSLKRKDRSPIF 685
            |  ::||..::|...|.:.|     ||..|......||:::|.....|..|.:||::||..:|.|
Mouse   253 Y--SSERGGLLVGVLRCVHL-----APMDANGYSDPFVRLFLHPSSGKKSKYKTSVRRKTLNPEF 310

  Fly   686 NESMIFSVPPPSLTTTQLRVTVFGVTTSGVTP-LGHIVAGSCAVGKGLRHWHQMLSSLRKPVAMW 749
            ||...::.....|....|.|:|:......... :|.:.....|.|:.||||.:.|......:.:|
Mouse   311 NEEFFYAGHREELAQKALLVSVWDYDLGTADDFIGGVQLSGRASGERLRHWRECLGHCDHRLELW 375

  Fly   750 HVL 752
            |:|
Mouse   376 HLL 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	29/129 (22%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	40/142 (28%)
Doc2g	NP_068563.2	C2A_Rabphilin_Doc2	84..209	CDD:176000	34/150 (23%)
		C2	246..378	CDD:472691	38/138 (28%)