Protein Alignment Syt12 and syt2a

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_696277.2
• Gene: syt2a / 567877
• ZFINID: ZDB-GENE-060503-315
• Length: 430
• Species: Danio rerio
• Alignment Length: 310
• Identity: 100/310 - (32%)
• Similarity: 158/310 - (50%)
• Gaps: 37/310 - (11%)

  Fly   483 GYLCVGLNYDQMSISNEGMELTVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTL 547
            |.|...|:|| .|.|    :|||.:|:|..|:...|..:.|.:|:::::||......|||.|.||
Zfish   149 GKLQFSLDYD-FSAS----QLTVGILQAADLLSMDSGGTSDPYVKVFILPDKKKKYDTKVHKKTL 208

  Fly   548 TPSYNESFDFWL-HKRQARHSLWFHLY--HNGPAHTLIGEAEMEIG--EMPRPITTWIPLSDSRK 607
            .|.:||:|.|.: .......:|...:|  .....|.:|||.::.:.  ::.:||..|..|..:.|
Zfish   209 NPVFNETFHFKIPFTEMGGKTLVMSVYDFDRFSKHDVIGEVKIPMNTLDLAQPIEQWRDLDSAEK 273

  Fly   608 CN-ARWGELMFSLSYLPTAERLTIVVVKARNL-KLD-GEQPAPESAETVHSVFVKVYLMDKDRKV 669
            .. .:.|::..||.|:|||.:|||.:::|:|| |:| |....|         :||::|:...:::
Zfish   274 EEPEKLGDICISLRYVPTAGKLTICILEAKNLKKMDVGGLSDP---------YVKIHLLQNGKRL 329

  Fly   670 LKKRTSLKRKDRSPIFNESMIFSVPPPSLTTTQLRVTVFGVTTSGVT-PLGHIVAGSCAVGKGLR 733
            .||:|::|:...:|.:|||..|.:|...:...|..:||......|.. .:|.|..||.|.|..||
Zfish   330 KKKKTTVKKNTLNPYYNESFSFEIPQDQMQKIQAVITVLDYDKIGKNDAIGKIWVGSKAQGTELR 394

  Fly   734 HWHQMLSSLRKPVAMWHVLRRAVNQPIFTGGAEAVVAAMQNTLQRSTAKR 783
            ||..||::.|:|:|.||.|:           .|..|.|   ||...|||:
Zfish   395 HWSDMLANPRRPIAQWHPLK-----------PEEEVDA---TLAALTAKK 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	31/103 (30%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	51/143 (36%)
syt2a	XP_696277.2	Syt2_N	5..>94	CDD:409249
		C2A_Synaptotagmin-1-5-6-9-10	148..270	CDD:176031	39/125 (31%)
		C2B_Synaptotagmin-1	279..414	CDD:176047	51/143 (36%)