Protein Alignment Syt12 and si:ch211-266g18.6

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_005169912.1
• Gene: si:ch211-266g18.6 / 565707
• ZFINID: ZDB-GENE-131121-599
• Length: 1009
• Species: Danio rerio
• Alignment Length: 949
• Identity: 171/949 - (18%)
• Similarity: 308/949 - (32%)
• Gaps: 309/949 - (32%)

  Fly    47 LSNHKQKLFHANGYMASIQSGSEFLLSTSGSFKRFDTIDKEDYNRSQQTHQTHLFLMNGGGAVSI 111
            :||.|:||       .:....:.||..|....|...|..||               ::||...::
Zfish   156 VSNKKEKL-------RAETDANPFLNGTDPGHKSTKTQPKE---------------LSGGQTTTV 198

  Fly   112 TGSSSALQAT-----TAMWHLPRSGIKIPP-----------------PPDRPAP----------- 143
            ...||.:|.|     |.....||..:.:||                 .|:...|
Zfish   199 FPFSSPVQDTKPERSTTKNPEPRRKVSLPPALQRDQSFEENWVKISLEPNTVKPVHDENNSSGIK 263

  Fly   144 ---------------SPNSAAAAGKTVTF---------------SLS------------------ 160
                           ||.::....|.|..               ||:
Zfish   264 LKEVKPHIKNIQDTSSPETSHTESKNVLLKSGSPMKEFHFQPQTSLAFTSHGPELTTHSAHGDSK 328

  Fly   161 QVNEVIMPGEQVTSNDQERRSCL-----RQNGGTAGGAGGGGVLPQPLEAPPPPRLTASTSVNLS 220
            :||:.....:..||.||:   ||     |::.....|         ||:         |.:|...
Zfish   329 EVNKFSNAFQNSTSTDQQ---CLAELTFRESESDKAG---------PLD---------SANVRDK 372

  Fly   221 GTAIPRPIAKRQVSTQPANNSGCQPE--QTVVTPM------------------REGERKAPALK- 264
            |:...|.|...:.|:......|....  ..|.|.|                  .|.|.::|:||
Zfish   373 GSLASRDIVNDEASSDRKGGEGKNVSIGFLVETDMDQAVEHLTGEEEINKHFSAEEESQSPSLKW 437

  Fly   265 ----------------------------RRN------SSTNPFLCESTEQIPSNPISEPL----- 290
                                        ::|      .:|...||:.|.|...:...:.:
Zfish   438 GIEMDSHEFPQVKDASSDFGDDVQVQIEKKNENELLYQTTGVKLCDKTVQSDLDSCEDKVKLRSY 502

  Fly   291 -NATVASLEKTTISTSECTPITAPLETPNGPISTDTPSTIHHNGNPFV--------------ERE 340
             |.|::.:.:...|.::...:....|..:...|...|....|..:...              ..|
Zfish   503 NNQTLSEISQDIFSMTDDGKLVHIREDKHMDKSVPEPIKPAHPSDDVAGFGQDSSEIKVDVDSAE 567

  Fly   341 SLSSRLLKIHNTTNPFTGLSQRVKGPHLLQKTISEDYLFRKLGVNCPMANGNGT----------- 394
            :.|..||.:       ...:|:.: |.:||...:::            .|..||
Zfish   568 TKSDVLLNV-------LARAQKTR-PPVLQNITNQE------------PNLEGTDDTVPSIVIVP 612

  Fly   395 --GPGSGHVNGNGNGTWSFGRSLLRQDSTLSLGMGLGRRNSSQV----------------SLDSH 441
              .|....:.||..|  :.....|.|.||        .:|.|.:                ||.|:
Zfish   613 SESPDPAEMKGNKRG--ALVLEALLQSST--------AKNPSYIADAWEDEGVNSDDDDTSLSSY 667

  Fly   442 AGSVPGSMDGINLERAISCDSVTSDSTLFLDQLDQPYTQITGYLCVGLNYDQMSISNEGMELTVS 506
             ||...|..|.:.......|...|..:::.|..|....::.|.:...:.|..:.      ||.:.
Zfish   668 -GSDLSSRKGFSASALSLTDRTGSLLSVYSDAGDFGTVEVQGSVEFAVMYSPVG------ELIIM 725

  Fly   507 VLEAKGL-ICPFSVESLDTFVRIYLVPD--HPGAMQTKVVKGTLTPSYNESFDFWLHKRQ-ARHS 567
            :.:.:.| |.....:..|.:|:.||.||  .....:|.:.|.|:.|.:.||..:.:::.: ...|
Zfish   726 IEQCQDLAIANPRKQRTDPYVKTYLYPDKSRRSKRKTTIKKRTVNPVFVESLRYKVNREELPEKS 790

  Fly   568 LWFHLYHNGP--AHTLIGEAEMEI--GEMPRPITTWIPLSDSRKCNARW----GELMFSLSYLPT 624
            |...::||..  .:..:|:.|:..  .:......||..|......||..    |.|..||.|:|:
Zfish   791 LNLSVWHNDSRGRNVFLGQVELSFRTWDWGHEALTWYNLQPKTSENAETKESNGLLSVSLKYVPS 855

  Fly   625 AE---------RLTIVVVKARNLKLDGEQPAPESAETVHSVFVKVYLMDKDRKVLKKRTSLKRKD 680
            |.         .:.:.:.:|:.|:    :..|:..::    |||.|::...||..:::|.:.:|.
Zfish   856 ASTGGSKSSTGEIHVWLREAKELR----RLKPQGVDS----FVKCYILPDTRKKSRQKTRVVKKT 912

  Fly   681 RSPIFNESMIF-SVPPPSLTTTQLRVTVFGVTTSGVTPLGHIVAGSCAVGKGLRHWHQM--LSSL 742
            :.|::|.:|:: ......:|.....:||:...|.....||.:   ..::|.|..:..::  :.|:
Zfish   913 QDPVYNHAMVYDGFKTGEVTEACCELTVWDHNTLANQFLGGV---RLSLGTGQSYGKKVDWMDSV 974

  Fly   743 RKPVAMWHVLRRAVNQPIFTGGAEAVVAAMQNTLQRSTA 781
            .:.|.:|..:..:.|.  :..|...:.:||  |.::||:
Zfish   975 DEEVQIWKRMLASPNS--WVEGELPLRSAM--TPRKSTS 1009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	23/106 (22%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	32/156 (21%)
si:ch211-266g18.6	XP_005169912.1	C2A_SLP-1_2	707..830	CDD:176039	26/128 (20%)
		C2B_SLP_1-2-3-4	843..999	CDD:175987	34/168 (20%)