Protein Alignment Syt12 and rph3ab

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_073763702.1
• Gene: rph3ab / 563377
• ZFINID: ZDB-GENE-090706-3
• Length: 602
• Species: Danio rerio
• Alignment Length: 674
• Identity: 142/674 - (21%)
• Similarity: 228/674 - (33%)
• Gaps: 207/674 - (30%)

  Fly   162 VNEVIMPGEQVTSNDQER--------------------RSCLRQNGGTAGGAGGGGVLPQPLEAP 206
            :|.||...|::.:.:|||                    ..|| ..|...||||...|:.:..
Zfish    44 INNVIARAEKMEAMEQERIGRLVNRLDNMKKTVCGDGVSRCL-LCGEQLGGAGDRAVVCEDC--- 104

  Fly   207 PPPRLTASTSVNLSGTAIPRPIAKRQVSTQPA---NNSGC-----QPEQTVVTPMREGERKAPAL 263
               :....|...:.....||.:...::.::..   ..||.     .|:|.:.:||       |..
Zfish   105 ---KKNMCTKCGVQTNTRPRSVWLCKICSEQREVWKRSGAWFFKGLPKQFLPSPM-------PIS 159

  Fly   264 KRRNSSTNPFLCESTEQIPSNPISEPLNATVASLEKTTISTSECTPITAPLETPNGPISTDTPST 328
            |.:.        .|..|.|:.|             ..|:.|.  .|:|||....|.||:...|..
Zfish   160 KPKE--------RSPHQTPAAP-------------PVTMQTQ--APVTAPEPAVNPPIAPKPPVA 201

  Fly   329 IHHNGNPFVERESLSSRLLKIHNTTNPFTGLSQRVKGPHLLQKTISEDYLFRKLGVNCPMANGNG 393
                                              .|..||..::.|||              |:.
Zfish   202 ----------------------------------PKPAHLQTQSFSED--------------GDP 218

  Fly   394 TGPGSGHVNGNGNGTWSFGRSLLRQDSTLSLGMGLGRRNSSQVSLDSHAGSVP----GSMDGINL 454
            ..|.:..|               ....|:::.......:|:...|:|..|..|    ||.|...|
Zfish   219 ASPQNTPV---------------MMKKTVNVHAARPVSSSTAAGLESDRGVYPPLSSGSADREEL 268

  Fly   455 ERAIS--------CDSVTSDSTLFLDQLDQPYTQITGYLCVGLNYDQMSISNEGMELTVSVLEAK 511
             :::|        ..||..|..  .:..|.......|.|...|.|||.:.|     |..::::||
Zfish   269 -KSVSPRVAQHQNAPSVDDDDE--ANSYDSDEATTLGSLEFTLLYDQGNSS-----LHCNIIKAK 325

  Fly   512 GLICPFSVESL-DTFVRIYLVPDHPGA-----MQTKVVKGTLTPSYNESF------DFWLHKRQA 564
            || .|.....| |.:|:::|:   |||     ::||.::.|..|::||:.      |..:.::..
Zfish   326 GL-KPMDSNGLADPYVKLHLL---PGASKSTKLRTKTLRNTRNPTWNETLVYHGLTDEDMQRKTL 386

  Fly   565 RHSLWFH--LYHNGPAHTLIGEAEMEIGEM--------------------------PRPITTWIP 601
            |.|:...  ..||    ..|||..:.:.::                          .|.||.:..
Zfish   387 RLSVCDEDKFGHN----EFIGETRVALKKLKINQKKNFNICLERVVQTKRSSTAGGARGITLYED 447

  Fly   602 LS--DSRKCNARWGELMFSLSYLPTAERLTIVVVKARNLKLDGEQPAPESAETVHSVFVKVYLMD 664
            .:  |..:...| |.::.||.|.....||.:.||:..:|       |...|......|||:.|..
Zfish   448 ETGKDGSELEER-GRILISLMYSTQLGRLIVGVVRCVHL-------AAMDANGYSDPFVKICLKP 504

  Fly   665 KDRKVLKKRTSLKRKDRSPIFNESMIFSVPPPSLTTTQLRVTVFGVTTSGVTP-LGHIVAGSCAV 728
            ...|..|.:|.:|:|..:|.|||...:.:....|....|.::|:......... :|....|..|.
Zfish   505 DMGKKAKNKTQIKKKTLNPEFNEEFSYEIKHAELAKKTLDISVWDYDIGKCNDYIGGCQLGITAK 569

  Fly   729 GKGLRHWHQMLSSLRKPVAMWHVL 752
            |:.|:||::.|.:..|.:..||.|
Zfish   570 GERLKHWYECLKNKDKKIERWHTL 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	30/138 (22%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	39/142 (27%)
rph3ab	XP_073763702.1	None