Protein Alignment Syt12 and syt14b

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_068071587.1
• Gene: syt14b / 561547
• ZFINID: ZDB-GENE-041014-36
• Length: 738
• Species: Danio rerio
• Alignment Length: 629
• Identity: 129/629 - (20%)
• Similarity: 215/629 - (34%)
• Gaps: 147/629 - (23%)

  Fly   230 KRQVSTQPANNSGCQPEQT-----VVTPMRE-----GERKAPALKRRNSSTNPFLCESTEQIPSN 284
            ||:...||:..|..|...|     .|..:.|     |:.|......:.::.......|.|:..|.
Zfish   148 KRKDPNQPSQTSDNQTSNTEQESKEVGTLEESTSLSGKHKKEGDHHKENANGVHTSNSQEEQDSQ 212

  Fly   285 PISEPLNATVASLEKTTISTSECTPITAPLETPNGPISTDTPSTIHHNGNPFVERESLSSRLLKI 349
            .:|...:.:.:::::...:.||      .:|.....:|.:...|....|..|.:.|...:    :
Zfish   213 EMSGDPDTSTSNIDRNGENCSE------KIEEDEDEVSHEEGKTQKKKGKVFSDEEQEEA----V 267

  Fly   350 HNTTNPFTGLSQRVKGPHLLQKTISEDYLFRKLGVNCPMANGNGTGPGS------------GHVN 402
            .::.|      .:.|.               |...|....:|.....||            .|..
Zfish   268 QDSKN------SKAKS---------------KAKKNKECKDGGCAEKGSESEDETQKKHKDSHQQ 311

  Fly   403 GNGNGTWSFGRSLLRQDSTLSLGMGLGRRNSSQVSL----------------------DSHAGS- 444
            .:|   |. .|....:|.:......|.:|.....||                      ||..||
Zfish   312 RSG---WR-NRDEENEDCSSEASAELVKRKKGSSSLNELQPPPYRDKDDVKRGSRGRSDSAEGSG 372

  Fly   445 ---VPGSMDGINLERAISC---DSVTSDSTLFL---DQLDQPYTQI--------TGYLCVGLNYD 492
               ..|:.|..:.|..::.   :...||||..|   |.|..|..:.        .|.|.|...||
Zfish   373 SEISEGTEDPEDTESYLNKGYEEDAPSDSTAVLGPEDSLIPPLPESYEPEALGKYGTLDVAFEYD 437

  Fly   493 QMSISNEGMELTVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTLTPSYNESFDF 557
            ...     ..|.|:|..|..:....|..::...|.:.|:|......:|.|.||. .|.:.|:|.|
Zfish   438 PGE-----QRLAVTVTAATDIPTLKSTGNISWQVHLVLLPTKKQRAKTGVQKGP-CPVFTETFRF 496

  Fly   558 WLHKRQA--RHSLWFHLY--HNGPAHTLIGEAEMEI------GEMPRPIT----TWIP-----LS 603
            ...:..|  .:::.|.||  .......::||....:      |::..|:|    |.:|     :|
Zfish   497 SCVEEDALGDYAVRFRLYSVRRMKKEKVLGEKVFYLTKLNLQGKLALPVTLEPGTSVPGCGSVVS 561

  Fly   604 DSRKCNA---------RWGELMFSLSYLPTAERLTIVVVKARNLKLDGEQPAP------------ 647
            .||...|         ...||:..|.|..|..||:..|:|..:.|.......|
Zfish   562 VSRSAGALSCRSTGESSIPELLLGLLYNSTTGRLSAEVIKGSHFKNSASDKLPIGLFCCVKHFIS 626

  Fly   648 ESAETVHSVFVKVYLMD-KDRKVLKKRTSLKRKDRSPIFNESMIFSVPPPSLTTTQLRVTVFGVT 711
            .....:...:||:.::| |.:::.|.:||:.|...:|.:.|:.:|.|....|:...|:|:|:...
Zfish   627 GQLYIMRDTYVKLTMLDSKGKEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSEVTLQVSVYSRR 691

  Fly   712 TS--GVTPLGHIVAG-SCAVGKGLRHWHQMLSSLRKPVAMWHVL 752
            :|  ....:|.:..| :....:...||.||..|..:.|..||.|
Zfish   692 SSMKRRERVGWVALGLNSTTEEQEEHWTQMKESEGQQVCHWHTL 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	27/117 (23%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	39/157 (25%)
syt14b	XP_068071587.1	2A1904	<59..324	CDD:273344	34/210 (16%)
		C2A_Synaptotagmin-14_16	426..549	CDD:176035	30/128 (23%)
		C2B_Synaptotagmin-14_16	579..736	CDD:176053	39/157 (25%)