Protein Alignment Syt12 and Syt5

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001347350.1
• Gene: Syt5 / 53420
• MGIID: 1926368
• Length: 386
• Species: Mus musculus
• Alignment Length: 403
• Identity: 115/403 - (28%)
• Similarity: 184/403 - (45%)
• Gaps: 85/403 - (21%)

  Fly   394 TGPGSGHVNGNGNGTWSFGRSLLRQDSTLSLGMGL------------------GRRNSSQVSLDS 440
            |.|.|..:.......|..        :|:.||.||                  |:::.:|..:
Mouse    15 TPPDSSRIRQGAVPAWVL--------ATIVLGSGLLVFSSCFCLYRKRCRRRMGKKSQAQAQV-- 69

  Fly   441 HAGSVPGSMDGINLERAISCDSVTSDSTLFLDQLDQ----PYTQIT-----GYLCVGLNYDQMSI 496
            |...|.      .|.|:. .|.|..:    :::||:    |..|::     |.|...|:||..:
Mouse    70 HLQEVK------ELGRSY-IDKVQPE----IEELDRSPSMPGQQVSDKHQLGRLQYSLDYDFQT- 122

  Fly   497 SNEGMELTVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTLTPSYNESFDF---- 557
                .:|.|.:|:|:||.......|.|.:|.:||:||.....:|||.:.||.|.:.|:|.|
Mouse   123 ----GQLLVGILQAQGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGETFAFKVPY 183

  Fly   558 -WLHKRQARHSLW-FHLYHNGPAHTLIGEAEMEIG--EMPRPITTW-----IPLSDSRKCNARWG 613
             .|..|....::: |..:....|   |||..:.:.  .:.||:..|     .|..:..|.    |
Mouse   184 VELGGRVLVMAVYDFDRFSRNDA---IGEVRVPMSSVNLGRPVQAWRELQVAPKEEQEKL----G 241

  Fly   614 ELMFSLSYLPTAERLTIVVVKARNL-KLD-GEQPAPESAETVHSVFVKVYLMDKDRKVLKKRTSL 676
            ::.|||.|:|||.:||::|::|:|| |:| |....|         :|||:|:...:||.||:|::
Mouse   242 DICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDP---------YVKVHLLQGGKKVRKKKTTI 297

  Fly   677 KRKDRSPIFNESMIFSVPPPSLTTTQLRVTVFGVTTSGVT-PLGHIVAGSCAVGKGLRHWHQMLS 740
            |:...:|.:||:..|.||...:...|:.:||......|.. .:|.:..|:...|.|||||..||:
Mouse   298 KKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAVGGAGLRHWADMLA 362

  Fly   741 SLRKPVAMWHVLR 753
            :.|:|:|.||.||
Mouse   363 NPRRPIAQWHSLR 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	32/111 (29%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	53/143 (37%)
Syt5	NP_001347350.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		3/5 (60%)
		Syt1_2_N	6..76	CDD:425364	13/76 (17%)
		C2	108..230	CDD:472691	37/129 (29%)
		C2	240..374	CDD:472691	53/146 (36%)