Protein Alignment Syt12 and syt9b

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001003985.1
• Gene: syt9b / 445476
• ZFINID: ZDB-GENE-040822-6
• Length: 517
• Species: Danio rerio
• Alignment Length: 540
• Identity: 143/540 - (26%)
• Similarity: 221/540 - (40%)
• Gaps: 141/540 - (26%)

  Fly   252 PMREGERKAPALKRRNSSTNPFLCESTEQIPSNPISEPLNATVASLEKTTISTSECTPITAPLET 316
            |.|  :|..|:||.:.....|.|.|                 |..||:......|..| .|||..
Zfish    82 PWR--DRFLPSLKDQQGEQQPVLAE-----------------VEGLEREYSEDFEKDP-NAPLVL 126

  Fly   317 PNGPISTDTPSTIHHNGNPFVERESLSSRLLKIHNTTNPFTGLSQRVKGPHLLQKTISEDYLFRK 381
            |...:...     |.:.:..:|.::.:..|..||     ...:.::|..|   ..::..:.:.|:
Zfish   127 PESAMKIS-----HTSPDIQLEAQTKAKELNHIH-----IARVQRQVTEP---TSSVRHNSIRRQ 178

  Fly   382 LGVNCPMANGNGTGPGSGHVNGNGNGTWSFGRSLLRQDSTLSLGMGLGRRNS---SQVSLDSHAG 443
            :.|:.|                      .|..:..::..::: |.||||...   .|.|:|:..|
Zfish   179 MNVSNP----------------------DFNMAQFQRQESIT-GPGLGRIKPELYKQRSVDTDDG 220

  Fly   444 SVPGSMDGINLERAISCDSVTSDSTLFLDQLDQPYTQITGYLCVGLNYDQMSISNEGMELTVSVL 508
                       .||.||                      |.|...:.||     .:..:|.|.:.
Zfish   221 -----------RRADSC----------------------GRLHFIIKYD-----CDLEQLIVKIH 247

  Fly   509 EAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTLTPSYNESFDFWL-HKRQARHSLWFHL 572
            .|:.|.......:.|.:|:|||:||.....||||.:.||.|.::|.|.|.: :.......|.|.:
Zfish   248 RAQDLPAKDFTGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPIFDEVFLFPVAYGELPTRKLHFSV 312

  Fly   573 Y--HNGPAHTLIGEAE----MEIGEMPRPITTWIPLSDSRKC---------NARWGELMFSLSYL 622
            |  .....|.:||:..    :::.:.|:         ::|.|         |...|:|||||.||
Zfish   313 YDFDRFSRHDVIGQVVVDNFLDLPDFPQ---------ETRLCRDILYVSADNVDLGDLMFSLCYL 368

  Fly   623 PTAERLTIVVVKARNLKLDGEQPAPESAETVHSVFVKVYLMDKDRKVLKKRTSLKRKDRSPIFNE 687
            |||.||||.::||||||......|.:.       :|||.||...|::.|::||.||...:|::||
Zfish   369 PTAGRLTITIIKARNLKAMDITGASDP-------YVKVSLMCDGRRLKKRKTSTKRNTLNPVYNE 426

  Fly   688 SMIFSVPPPSLTTTQLRVTVFGVTTSGVTPLGH-IVAGSCAVGK-----GLRHWHQMLSSLRKPV 746
            :::|.|||.::....|.:.|.....     :|| .|.|.|.||.     |..||::||:..|||:
Zfish   427 AIVFDVPPENIDQISLLIAVMDYDR-----VGHNEVIGICHVGNRAPSLGRDHWNEMLTYPRKPI 486

  Fly   747 AMWHVLRRAVNQPIFTGGAE 766
            |.||.|...|.|.. |||::
Zfish   487 ARWHQLVEWVGQST-TGGSQ 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	28/105 (27%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	60/146 (41%)
syt9b	NP_001003985.1	C2	226..350	CDD:472691	35/159 (22%)
		C2B_Synaptotagmin-3-5-6-9-10	359..492	CDD:176048	60/144 (42%)