Protein Alignment Syt12 and Syt14

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Alignment Length: 639
• Identity: 143/639 - (22%)
• Similarity: 222/639 - (34%)
• Gaps: 200/639 - (31%)

  Fly   173 TSNDQE----RRSCLR-----QNGGTAGGAGGGGVLPQPLEAPPPPRLTASTSVNLSGTAI---P 225
            ||:|.|    ||  ||     |.|...||.|.|.....||.|.......|..|.:|....:   |
  Fly    78 TSSDSEEDILRR--LRWHQQHQLGEKPGGYGLGISQANPLTAQSFNYHQAGASADLQRVTVSRDP 140

  Fly   226 RPIAKRQVSTQPANNSGCQPEQTVVTPMREGERKAPALKRRNSSTNPFLCESTE-QIPSNPISEP 289
            ..||:|.....|:::|.|                         |:|    :|.| .:.|:
  Fly   141 LAIAERGKVGIPSSHSEC-------------------------SSN----DSMEVSVDSH----- 171

  Fly   290 LNATVASLEKTTISTSECTPITAPLETPNGPISTDTPSTIHHNGNPFVERESLSSRLLKIHNTTN 354
             ...:..|.|.|        .|.|           .|:|...  ||..|..:.:..|...|..
  Fly   172 -TGVLTGLSKAT--------TTVP-----------HPATAFR--NPCGEHRAKTQALRYQHRV-- 212

  Fly   355 PFTGLSQRVKGPHLLQKTISEDYLFRKLGVNCPMANGNGTGPGSGHVNGNGNGTWSFGRSLLRQD 419
                   .|..|..|.|.       |...:..||.|...       :|.|
  Fly   213 -------NVAAPPKLDKE-------RDNVLVVPMVNAYS-------INNN--------------- 241

  Fly   420 STLSLGMGLGRRNSSQVSLDSHAGSVPGSMDGINLERAISCDSVTSDSTLF-LDQLDQPYTQITG 483
                        |:|..:.::|..|  .:.|...|.......|:.||..|. :||.:....:...
  Fly   242 ------------NNSITTSNNHPSS--NNNDDEPLFDTSDLRSIKSDDLLVGVDQKEPAVQRGPI 292

  Fly   484 YLCVGLNYDQMSISNEGMELTVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTLT 548
            .|.:.|.||...     .::||.|::||.|....|.::..|.||:.::|.....::||:..|. .
  Fly   293 ELELSLLYDAPM-----RKMTVHVMQAKNLPPLGSGQTTHTQVRMLMLPSKKQKLKTKIRSGE-N 351

  Fly   549 PSYNESFDFWLHKRQARH----SLWFHLY--HNGPAHTLIGEAEMEIGEMPRPITT--WIPLSDS 605
            |.|.||  |.||:.....    .|...||  .......|||||.:....:...:.|  |:|| :.
  Fly   352 PQYMES--FLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLELETNLWLPL-EP 413

  Fly   606 RKCNARWG--------------------------ELMFSLSYLPTAERLTIVVVKA---RNLKLD 641
            |..::..|                          ||:..|||.....||::.::|.   |:|.|:
  Fly   414 RNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSLSLN 478

  Fly   642 GEQPAPESAETVHSVFVKVYLMDK-DRKVLKKRTSLKRKDRSPIFNESMIFSVPPPSLTTTQLRV 705
               .||::       :||:.::.. .:::.:.:||::|...:|:|.|:..|.|....|....|.:
  Fly   479 ---KAPDT-------YVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMI 533

  Fly   706 TVF----------------GVTTSGVTPLGHIVAGSCAVGKG--LRHWHQMLSS 741
            :|:                |:.:||...:.| .|..|.:.||  |..||.::.|
  Fly   534 SVYAKRHMKKNEMVGWFSLGLNSSGSEEVAH-WADVCEMPKGEMLARWHVLVDS 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	31/106 (29%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	39/178 (22%)
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	37/130 (28%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	37/148 (25%)