Protein Alignment Syt12 and Sytalpha

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001188832.1
• Gene: Sytalpha / 35068
• FlyBaseID: FBgn0261089
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 466
• Identity: 123/466 - (26%)
• Similarity: 193/466 - (41%)
• Gaps: 85/466 - (18%)

  Fly   315 ETPNGPISTDTPSTIHHNGNPFVERESLSSRLLKIHNTTNPFTGLSQRVKGPHLLQKTISEDYLF 379
            |.|.|..|         :||    ..:||...||..: .:|...:...|.....:|:.:|
  Fly    90 EVPRGKYS---------SGN----AGNLSPTSLKSED-NDPAFWVPASVTSTAAIQQQVS----- 135

  Fly   380 RKLGVNCPMANGNGTGPGSGHVNGNGNGTWSFGRSLLRQDSTLSLGMGLGRRNSSQVSLDSHAGS 444
                 |....:...|.|           |.|...:.|...||.|:.:.   |:...|.|..|. |
  Fly   136 -----NTTEESAPPTSP-----------TGSLKSNTLSYCSTTSVPIA---RSDKHVVLAMHP-S 180

  Fly   445 VP--GSMDGINLERAISCDSVTSDSTLFLDQLDQPYT-------QITGYLCVGLNYDQMSISNEG 500
            .|  .||:.       ..|....|.||:... .||.|       ::.|.|.|.|.||.:     |
  Fly   181 RPRVSSMNA-------KLDHTKIDMTLYRSH-SQPKTINPVSLNEVRGNLHVSLGYDPV-----G 232

  Fly   501 MELTVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTLTPSYNESFDF-----WLH 560
            ..|.|.:|||:.|.......:.|.:.::.|:||.....||::.|.||.|.::|.|.|     .:.
  Fly   233 GLLNVRLLEAQNLQPRQFSGTADPYAKVRLLPDKKNFWQTRIHKRTLNPVFDEQFVFEVTAGVID 297

  Fly   561 KRQARHSLW-FHLYHNGPAHTLIGEAEMEIG--EMPRPITTWIPLS--DSRKCNARWGELMFSLS 620
            ||.....|: |..|..   |..||.:::.:.  ::...:..|.|||  .::......|::|.||:
  Fly   298 KRTVEILLYDFDAYSR---HVCIGGSKLHLANLDLSEQLKLWTPLSSASAQDMKVDLGDIMVSLA 359

  Fly   621 YLPTAERLTIVVVKARNLKLDGEQPAPESAETVHSVFVKVYLMDKDRKVLKKR-TSLKRKDRSPI 684
            |||:||||.:|::|||||::      .:.|......:|||.|:....|.:||| |.::|...:|:
  Fly   360 YLPSAERLMVVLIKARNLRI------VDDARNSSDPYVKVTLLGPGGKKIKKRKTGVQRGTLNPV 418

  Fly   685 FNESMIFSVPPPSLTTTQLRVTVF--GVTTSGVTPLGH-IVAGSCAVGKGLRHWHQMLSSLRKPV 746
            :||::.|.|...:|....|..||.  |:..|... ||. ::..|..|....:.:.:.:...:...
  Fly   419 YNEALAFDVAKETLKNCVLEFTVVHDGLLGSSEI-LGRTLIGNSPEVRTEEKIFFEEVFRAKNAT 482

  Fly   747 AMWHVLRRAVN 757
            |.|..|:...|
  Fly   483 AQWVPLQEPAN 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	28/106 (26%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	45/144 (31%)
Sytalpha	NP_001188832.1	C2A_Synaptotagmin-8	218..341	CDD:176033	37/130 (28%)
		C2B_Synaptotagmin	352..488	CDD:175975	45/142 (32%)