Protein Alignment Syt12 and Syt1

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Alignment Length: 530
• Identity: 138/530 - (26%)
• Similarity: 220/530 - (41%)
• Gaps: 126/530 - (23%)

  Fly   281 IPSNPISEPLNATVASLEKTTISTSECTPITAPLETPNGPI-STDTP-STIHHNGNPFVER---- 339
            :|.|..||            |.:..|..|  ||...|...: |.|.. ...||:....|:|
  Fly     1 MPPNAKSE------------TDAKPEAEP--APASEPAADLESVDQKLEETHHSKFREVDRQEQE 51

  Fly   340 -------ESLSSRLLKIHNTTNPFTGLSQRVKGPHLLQKTISEDYLFRKLGVNCPMANGNGTGPG 397
                   |:.|.|:.::.:||...|..:|        :.|.:...:.:|:
  Fly    52 VLAEKAAEAASQRIAQVESTTRSATTEAQ--------ESTTTAVPVIKKI--------------- 93

  Fly   398 SGHV---------NGNGNGTWS------------FG------RSLLRQDSTLSLGMGLGRR---- 431
             .||         ...|..||.            ||      |..|::..|..   |.|::
  Fly    94 -EHVGEVVTEVIAERTGLPTWGVVAIIILVFLVVFGIIFFCVRRFLKKRRTKD---GKGKKGVDM 154

  Fly   432 NSSQVSLDSHAGSVPGSMDGI--NLERAISCDSVTSDSTLFLDQLDQPYTQITGYLCVGLNYDQM 494
            .|.|:...::...|...|:.:  |.|..              |:.|:...|..|.|...|.||..
  Fly   155 KSVQLLGSAYKEKVQPDMEELTENAEEG--------------DEEDKQSEQKLGRLNFKLEYDFN 205

  Fly   495 SISNEGMELTVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTLTPSYNESFDF-- 557
            |.|     |.|:|::|:.|.......:.|.:|::||:||.....:|||.:.||:|.:||:|.|
  Fly   206 SNS-----LAVTVIQAEELPALDMGGTSDPYVKVYLLPDKKKKFETKVHRKTLSPVFNETFTFKS 265

  Fly   558 WLHKRQARHSLWFHL--YHNGPAHTLIGEAEMEIG--EMPRPITTWIPL--SDSRKCNARWGELM 616
            ..:......:|.|.:  :.....|..|||.::.:.  ::.:.|..|..|  .:......:.|::.
  Fly   266 LPYADAMNKTLVFAIFDFDRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQEKLGDIC 330

  Fly   617 FSLSYLPTAERLTIVVVKARNL-KLD-GEQPAPESAETVHSVFVKVYLMDKDRKVLKKRTSLKRK 679
            |||.|:|||.:||:|:::|:|| |:| |....|         :||:.:|...:::.||:||:|:.
  Fly   331 FSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDP---------YVKIAIMQNGKRLKKKKTSIKKC 386

  Fly   680 DRSPIFNESMIFSVPPPSLTTTQLRVTVFGVTTSGVT-PLGHIVAGSCAVGKGLRHWHQMLSSLR 743
            ..:|.:|||..|.||...:....|.|||......|.: |:|..:.|....|..||||..||:|.|
  Fly   387 TLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPR 451

  Fly   744 KPVAMWHVLR 753
            :|:|.||.|:
  Fly   452 RPIAQWHTLK 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	29/104 (28%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	54/143 (38%)
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364	22/125 (18%)
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	37/128 (29%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	54/143 (38%)