Protein Alignment Syt12 and Syt4

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_033334.2
• Gene: Syt4 / 20983
• MGIID: 101759
• Length: 425
• Species: Mus musculus
• Alignment Length: 360
• Identity: 100/360 - (27%)
• Similarity: 173/360 - (48%)
• Gaps: 56/360 - (15%)

  Fly   422 LSLGMGLGRR--NSSQVSLDSHAGSVPGSMDGINL---------ERAISCDSVTSDSTLFLDQLD 475
            |||.:.|.:|  |.:....:..|||   |.|..|:         :.|.|.:|:.|.::|..::..
Mouse    90 LSLHLDLEKRDLNGNFPKANPKAGS---SSDLENVTPKLFTETEKEANSPESLKSSTSLTSEEKQ 151

  Fly   476 QPYTQITGYLCVGLNYDQMSISNEGMELTVSVLEAKGLICPFSVE---SLDTFVRIYLVPDHPGA 537
            :.    .|.|.:.|.|     :.|.....|::.||:||  |...|   :.|.::::.::|:....
Mouse   152 EK----LGTLFLSLEY-----NFEKKAFVVNIKEAQGL--PAMDEQSMTSDPYIKMTILPEKKHR 205

  Fly   538 MQTKVVKGTLTPSYNESFDF----WLHKRQARHSLWFHL--YHNGPAHTLIGEA-------EMEI 589
            ::|:|::.||.|.::|:|.|    :.|.::.  ||.|.:  :.......:|||.       |:..
Mouse   206 VKTRVLRKTLDPVFDETFTFYGIPYPHIQEL--SLHFTVLSFDRFSRDDVIGEVLIPLSGIELSD 268

  Fly   590 GEMPRPITTWIPLSDSRKCNARWGELMFSLSYLPTAERLTIVVVKARNLKLDGEQPAPES-AETV 653
            |:|  .:|..|...:::|.:.| |||:.||.|..|...||:||:|||:|        |:| ...:
Mouse   269 GKM--LMTREIIKRNAKKSSGR-GELLVSLCYQSTTNTLTVVVLKARHL--------PKSDVSGL 322

  Fly   654 HSVFVKVYLMDKDRKVLKKRTSLKRKDRSPIFNESMIFSVPPPSLTTTQLRVTVF-GVTTSGVTP 717
            ...:|||.|....:::.||:|.:|:...:.:|||..:|.:|..||....:...|. ....|....
Mouse   323 SDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCESLEEISVEFLVLDSERGSRNEV 387

  Fly   718 LGHIVAGSCAVGKGLRHWHQMLSSLRKPVAMWHVL 752
            :|.:|.|:.|.|.|..||.::....|:.:|.||:|
Mouse   388 IGRLVLGATAEGSGGGHWKEICDFPRRQIAKWHML 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	29/114 (25%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	47/143 (33%)
Syt4	NP_033334.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..147		5/19 (26%)
		C2A_Synaptotagmin-4-11	153..279	CDD:176034	34/140 (24%)
		C2B_Synaptotagmin-4	288..423	CDD:176049	48/144 (33%)