Protein Alignment Syt12 and snt-2

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_497261.2
• Gene: snt-2 / 185680
• WormBaseID: WBGene00004922
• Length: 369
• Species: Caenorhabditis elegans
• Alignment Length: 419
• Identity: 101/419 - (24%)
• Similarity: 176/419 - (42%)
• Gaps: 106/419 - (25%)

  Fly   378 LFRKLGVNCPMANG----NGTGPGSGHVN-GNGNGTWSFGRSLLRQDSTLSLGMGLGRRNSSQVS 437
            :||.|...||:..|    ||..|...||: |||.......:.:..|.:            :|...
 Worm    12 VFRILSTCCPIRRGVPTSNGYHPRPKHVDIGNGAVPILSSKPITVQPT------------NSDYY 64

  Fly   438 LDSHAGSVPGSMDGINLERAISCDSVTSDSTLFLDQLDQPYTQITGYLCVGLNYDQMSISNEGME 502
            ...:.|::|.|..|..:::                         .|.:...:.||     .|..:
 Worm    65 EPVNNGTLPLSSSGALIKQ-------------------------YGNIHFRVEYD-----FEQSK 99

  Fly   503 LTVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTLTPSYNESFDFWLHKRQARHS 567
            |:|:::.|..|.........|.:|::|::|:.....:|::::.||.|:|||:|.|         |
 Worm   100 LSVTIVSASDLPAMDRNGMSDPYVKVYVLPERKQKFETRIIRNTLNPTYNETFQF---------S 155

  Fly   568 LWFHLYHNGPAHTLIGEAEM-----EIGEMPRP-------ITTWI--PL-----SDSRKCNARWG 613
            :.|:..|:.....::.:.:.     ::|::..|       |||.|  ||     .|.::|  |.|
 Worm   156 IPFNELHSKTLMLVVYDYDRLSKDDKMGQLSVPLESIDFGITTDIERPLQKPEKDDEKEC--RLG 218

  Fly   614 ELMFSLSYLPTAERLTIVVVKARNL-KLD-GEQPAPESAETVHSVFVKVYLMDKDRKVLKKRTSL 676
            ::.||..|.|....:|:.:::|||| |:| |....|         :||:||....:.:.||:||.
 Worm   219 DICFSTRYRPATGTVTLTIMEARNLKKMDVGGSSDP---------YVKIYLHHGRKLLSKKKTSR 274

  Fly   677 KRKDRSPIFNESMIFSVPPPSLTTTQLRVTVFGVTTSGVTP-LGHIVAGS-----------CAVG 729
            |.|..:|.:|||..|.:.|..:....|.|:|:......... :|.:..||           |:
 Worm   275 KYKTLNPYYNESFQFKIEPHMIEKVHLIVSVWDYDKMSKNDFIGEVTLGSKHLNLPQITHACS-- 337

  Fly   730 KGLRHWHQMLSSLRKPVAMWHVLRRAVNQ 758
               ..|.:|::| |:||..||.|:..:.:
 Worm   338 ---EQWAEMMTS-RRPVVQWHTLQERMEK 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	26/112 (23%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	45/154 (29%)
snt-2	NP_497261.2	C2	85..206	CDD:472691	32/134 (24%)
		C2B_Synaptotagmin-1	217..357	CDD:176047	45/154 (29%)