Protein Alignment Syt12 and sue-1

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_492083.2
• Gene: sue-1 / 184108
• WormBaseID: WBGene00006306
• Length: 537
• Species: Caenorhabditis elegans
• Alignment Length: 606
• Identity: 116/606 - (19%)
• Similarity: 203/606 - (33%)
• Gaps: 143/606 - (23%)

  Fly   223 AIPRPIAKRQVSTQP------ANNSGCQPEQTVVTPMREGERKAPALKRRNSSTNPFLCESTEQI 281
            |:..|..:|::...|      :::....|....::|.......||.|:||.|.         .|:
 Worm    14 ALLEPTCRRRLPMPPDTHLRRSSSPRILPTPPPLSPEYRCPSAAPHLERRPSG---------RQL 69

  Fly   282 PSNPISEPLNATVASLEKTTISTSEC--TPIT-APLETPNGP-----ISTDTPSTIHHNGNPFVE 338
            |..|.:|..|.|  ||.......|:|  :|:: .|..||:.|     ...|....:..:.....|
 Worm    70 PRPPTAELSNLT--SLAHNGPGNSQCSLSPVSLTPDPTPDEPEFYEEEDVDESEVVEEDYAQEEE 132

  Fly   339 RESLSSRLLKIHN---TTNPFTGLSQRVK--GPHLLQKTISEDYLFRKLGVNCP----MANGNGT 394
            .|.....:::..:   .|.|     :.::  .|.:|.....:.....|..|:.|    :.:.:.:
 Worm   133 EEGDDGEVVEYEDPVVVTPP-----EEIRRISPEILIAPPPQPRRMSKFSVHSPSIEQITSKSSS 192

  Fly   395 GPGSGHVNGNGNGTWSFGRSLLRQDSTLSLGMGLGRRNSSQVSLDSHAGSVPGSMDGINLERAIS 459
            .......:|.....:|....::.:::..::         .:.|:.|.:...|....|:.|   :.
 Worm   193 DTEDPIAHGLDPSLYSPNAPIIIENNNTAI---------HKTSVASSSSPTPQQPRGLGL---LH 245

  Fly   460 CDSVTSDSTLFLDQLDQPYTQITGYLCVGLNYDQMSISNEGMELTVSVLEAKG----------LI 514
            |..:                    |..|          .:.:.:||:.:||..          .:
 Worm   246 CSLL--------------------YFAV----------RKRLRVTVTKIEALAGELKPEMEIHAL 280

  Fly   515 CPFSVESLDTFVRIYLVPDHPGAMQTKVVKGTLTPSYNES--FDFWLHKRQARHSLWFHLYHNGP 577
            |..|:..|           ..|..||...|....|.:|..  ||...|:......:.....|.|.
 Worm   281 CKVSIPGL-----------KGGKEQTSETKRGRDPLFNHEFFFDNVTHEELDTKVVIITACHAGG 334

  Fly   578 AHTLIGEAEMEIGEMPRPITTWIPLSDSRKCNA----------------RWGELMFSLSYLPTAE 626
            .   |...|:.|||..      :||.|.|:.|.                :.|::..|......::
 Worm   335 G---IKGKEIVIGEAS------VPLRDIREMNTKKEIKFIEEIKGLVPKKLGKIYTSSIIEKDSK 390

  Fly   627 RLTIVVVKARNLKLDGEQPAPESAETVHSVFVKVYLMDKDRKVLKKRTSLKRKDRSPIFNESMIF 691
            ||||.:.|...|...|...||:       |.||:.| .:..|...|.:.:.:...|.::||:::|
 Worm   391 RLTINLKKVDALPKCGLIGAPD-------VCVKITL-TQGAKTQTKSSRVIKNTCSAVYNEAVMF 447

  Fly   692 --SVPPPSLTTTQLRVTVFGV--TTSGVTPLGHIVAGSCAVGKG-LRHWHQMLSSLRKPVAMWHV 751
              ......|..|.:.::|...  |.:|...:|....|..||.|. :..|......|.|.....|.
 Worm   448 LCGTSKNDLAQTSIVISVHDAQRTCTGDDTIGCAYLGIGAVDKSEIDQWKGTTEHLGKEYKGNHT 512

  Fly   752 LRRAVN-QPIFTGGAEAVVAA 771
            |:..:. .|:....|...|||
 Worm   513 LKAPITAPPVHVAEANDDVAA 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	23/110 (21%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	35/145 (24%)
sue-1	NP_492083.2	C2	242..349	CDD:472691	27/159 (17%)
		C2	389..513	CDD:472691	33/131 (25%)