Protein Alignment Syt12 and syt10

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_031754327.1
• Gene: syt10 / 116409668
• XenbaseID: XB-GENE-29099511
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 625
• Identity: 160/625 - (25%)
• Similarity: 241/625 - (38%)
• Gaps: 177/625 - (28%)

  Fly   199 LPQPLEA--PPPPRLTASTSVNLSGTAIPRPIAKRQVSTQPANNSGCQPEQTVVTPM-----REG 256
            ||:||.|  |||..::....   .|.::                  ||....:|:.:     .|.
 Frog     5 LPRPLPAQLPPPGAMSFHKE---DGVSL------------------CQKALQIVSELCLGGQVEW 48

  Fly   257 ERKAPALKRRNSSTNPFLCESTEQIPSNPISEPLNATVAS---LEKTTIS--------------- 303
            ::.:....|.|....           |..||..|.|.|.|   |....:|
 Frog    49 DKCSGIFPRTNQGAG-----------STDISVSLLAVVVSFCGLALLVVSLFVFWKLCRPCWRNK 102

  Fly   304 ----------TSECTPITAPLETPNGPISTDTPSTIHHNGNPFVERESLSSRLLKIHNTTNPFTG 358
                      ...|.| :||.|.|      |....|..||...|.   |....:||.:|:.....
 Frog   103 PLPGANHVAPPPPCVP-SAPPEVP------DDKKEIKQNGRQSVR---LQEAAMKISHTSPDIPA 157

  Fly   359 LSQRVKGPHL-----LQKTISEDYLFRKLGVNCPMANGNGTGPGSGHVNGNGNGTWSFGRSLLRQ 418
            ..|.....||     :|:.|:|                    |.|...:.      ||.|.|.||
 Frog   158 EVQSALKEHLMRHARIQRQITE--------------------PTSSSRHN------SFRRHLPRQ 196

  Fly   419 DSTLSLGMGLG----RRNSSQVSLDSHAGSVPGSMDGINLERAISCDSVTSDSTLFLDQLDQPYT 479
            ....|:...:|    :|..:..|:    |.:..     .|.:..|.||         :...:...
 Frog   197 MQVSSVDFSIGVEPLQRGETTTSI----GRIKP-----ELYKQKSVDS---------EDNKKEDV 243

  Fly   480 QITGYLCVGLNYDQMSISNEGMELTVSVLEAKGL----ICPFSVESLDTFVRIYLVPDHPGAMQT 540
            :..|.|...|.:|.     |...|.|.:::|..|    :|..|    |.:|:|||:||.....||
 Frog   244 KTCGKLNFSLQFDY-----ENELLVVKIVKALDLPAKDLCGTS----DPYVKIYLLPDRKKKFQT 299

  Fly   541 KVVKGTLTPSYNESFDFWL-HKRQARHSLWFHLY--HNGPAHTLIGEAEM----EIGEMPRPITT 598
            :|.:.||.|.:.|:|.|.: :.:.:...|.|.:|  .....|.:|||..:    |..::.|..|.
 Frog   300 RVHRKTLNPIFEETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEASDLSREATV 364

  Fly   599 WIPLSDSRKCNARWGELMFSLSYLPTAERLTIVVVKARNLK---LDGEQPAPESAETVHSVFVKV 660
            |..:..:...:...||:|:||.|||||.|:|:.|:|.||||   :.|..          ..:|||
 Frog   365 WKDIHCATSESVDLGEIMYSLCYLPTAGRMTLTVIKCRNLKAMDITGSS----------DPYVKV 419

  Fly   661 YLMDKDRKVLKKRTSLKRKDRSPIFNESMIFSVPPPSLTTTQLRVTVFGVTTSGVTPLGH-IVAG 724
            .||.:.|::.|::|:.|:...:||:||::||.:||.::....|.:||.....     :|| .|.|
 Frog   420 SLMCEGRRLKKRKTTTKKNTLNPIYNEAIIFDIPPENMDQVSLSITVMDYDR-----VGHNEVIG 479

  Fly   725 SC-----AVGKGLRHWHQMLSSLRKPVAMWHVLRRAVNQP 759
            .|     |.|.|..||::||:..|||:..||.|   |.||
 Frog   480 VCRTGVDAEGLGRDHWNEMLAYPRKPITHWHPL---VEQP 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	33/109 (30%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	56/149 (38%)
syt10	XP_031754327.1	C2A_Synaptotagmin-1-5-6-9-10	245..370	CDD:176031	38/133 (29%)
		C2B_Synaptotagmin-3-5-6-9-10	379..512	CDD:176048	56/147 (38%)