DRSC/TRiP Functional Genomics Resources

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Protein Alignment Syt12 and syt15

DIOPT Version :10

Sequence 1:NP_572878.1 Gene:Syt12 / 32290 FlyBaseID:FBgn0261085 Length:787 Species:Drosophila melanogaster
Sequence 2:XP_002941809.1 Gene:syt15 / 100496499 XenbaseID:XB-GENE-6050096 Length:420 Species:Xenopus tropicalis


Alignment Length:354 Identity:94/354 - (26%)
Similarity:158/354 - (44%) Gaps:53/354 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   426 MGLGRRNSSQVSLDSHAGSVPGSMDGINLERAISCD--------SVTSDSTLF---LDQLDQPYT 479
            :|||  |..::..||...:.|..     |.|:..|.        |:......|   .::.|.|..
 Frog    89 IGLG--NGERIQDDSEPYTAPDF-----LPRSSFCSLGGAYVVGSINPALYKFPEENEETDFPEG 146

  Fly   480 QITGYLCVGLNYDQMSISNEGMELTVSVLEAKGLICPFSVESLDTFVRIYLVPDHPGAMQTKVVK 544
            .| |.:...:.|:.     |...|.||:::.:.|  .|..:|.:.||:|:|:||....:|:|..:
 Frog   147 NI-GRIWFAVEYEL-----ETERLVVSLMKVRNL--QFGSDSCNPFVKIHLLPDERRHLQSKTKR 203

  Fly   545 GTLTPSYNESFDF-----WLHKRQARHSLWFHLYH--NGPAHTLIGEAEMEIGEM----PRPITT 598
            .|:.|.::|:|.|     .:|:|..|    |.:||  ....|.|:|:....:...    ...:..
 Frog   204 KTVNPQFDETFVFQVSGKTVHQRTLR----FSIYHVDKIKKHHLLGQVVFPLKNESLTDDENVVI 264

  Fly   599 WIPLS-DSRKCNARWGELMFSLSYLPTAERLTIVVVKARNLKLDGEQPAPESAETVHSVFVKVYL 662
            |..|. ::.:..:.:|.:.|||||.....|||:|:::|:.|:.      .|....:.|.||||..
 Frog   265 WRDLELENLEPPSEYGNIQFSLSYNDYLGRLTVVLLRAKGLQF------LEERGVISSAFVKVSF 323

  Fly   663 MDKDRKVLKKRTSLKRKDRSPIFNESMIFSVPPPSLTTTQLRVTVFGVTTSGVTP--LGHIVAGS 725
            |:.::.|..|:|:......:|::||:..|.|....|.|..|.:.|: ....|...  ||.:|.|.
 Frog   324 MNHNKLVKCKKTAAICGTANPVYNETFSFKVEHIGLDTASLSLAVY-QNAQGEKSHLLGRVVVGP 387

  Fly   726 CAV--GKGLRHWHQMLSSLRKPVAMWHVL 752
            ...  |:.|.||::||:..:..|..||.|
 Frog   388 YMYTRGRELEHWNEMLNKPKDLVKRWHAL 416

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Syt12NP_572878.1 C2 503..602 CDD:425499 29/109 (27%)
C2B_Synaptotagmin-12 612..753 CDD:176051 46/145 (32%)
syt15XP_002941809.1 TM_EGFR-like 7..32 CDD:213052
C2A_Synaptotagmin-15-17 149..269 CDD:176036 32/130 (25%)
C2B_Synaptotagmin-15 279..417 CDD:176054 46/145 (32%)
Blue background indicates that the domain is not in the aligned region.

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