Protein Alignment Syt12 and syt7b

DIOPT Version :10

• Sequence 1: NP_572878.1
• Gene: Syt12 / 32290
• FlyBaseID: FBgn0261085
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: XP_068078246.1
• Gene: syt7b / 100334336
• ZFINID: ZDB-GENE-090601-6
• Length: 654
• Species: Danio rerio
• Alignment Length: 753
• Identity: 181/753 - (24%)
• Similarity: 289/753 - (38%)
• Gaps: 211/753 - (28%)

  Fly   104 NGGGAVSITGSSSALQATTAM-----------WHLPRSGIKIPPPPDRPAPSPNSAAAAGKTVTF 157
            :|.|::|::....::..|..:           |...:.|::..|..: .|.:|:|.:.:|:.
Zfish     9 DGKGSLSLSVFLVSVGLTVCVVWLVALCGVCGWCQRKLGMRNKPGVE-TAGTPDSVSVSGRG--- 69

  Fly   158 SLSQVNEVIMPGEQ--VTSNDQER------RSCLRQNGGTAGGAGGGGVLPQPLEAPPP------ 208
                      .||.  :..||.:|      .||..|               |...:.||
Zfish    70 ----------RGENKAINHNDLDRDFWNNNDSCSVQ---------------QRWSSYPPKEFLLN 109

  Fly   209 ---------PRLTASTSV---NLSGTAIPRPIAKRQVSTQPANNSGCQPEQTVVTPMREGERKAP 261
                     ||||.:.|:   ...|.|:..|  .|..|...|..|.....||:.:.:..|..:
Zfish   110 MSPYAPYGDPRLTPNGSLEKGEAGGGAVGGP--SRSDSCIGAGTSRSGRWQTLQSHLHSGSLR-- 170

  Fly   262 ALKRRNSSTNPFLCESTEQIPSNPISEPLNATVASLEKTTISTSECTPIT------APL--ETPN 318
                                ||| ..:|..:|.::||....|.:...|:.      .||  :.|.
Zfish   171 --------------------PSN-FGDPSLSTTSTLEHIPSSAARPRPLVRQQSLQQPLTHQPPP 214

  Fly   319 GPISTDTPSTIHHNGNPFVERESLSSRLLKIHNTTNPFTGLSQRVKGPHLLQKTISEDYLFRKLG 383
            ||  .|.|:|              |..|.::|  |.|  |......||.               |
Zfish   215 GP--NDPPAT--------------SQSLGQLH--TGP--GGGGHRGGPR---------------G 244

  Fly   384 VNCPMANGNGT------------GPGS-----GHVNGNGNGTWSF--GRSLLRQDSTLSLGMGLG 429
            |....|....|            .|||     |.:...|....||  |:.::     |||.:||.
Zfish   245 VRGSPAGAGATRYRSGGGARSRSNPGSWDHMMGQIRTRGMDVKSFLEGKMVV-----LSLAIGLA 304

  Fly   430 RRNS-------SQVSLDSHA------GSVPGS------------MDGINLERAISCDSVTSDSTL 469
            .::.       .:...|:..      .:.|||            ....|...:...:|||||..:
Zfish   305 EQDDFANLPDLQEAPADTETPPTDKRSNKPGSSPKGQTPDESHRRTDANSSVSDLANSVTSDMLM 369

  Fly   470 FLDQLDQPYTQITGYLCVGLNYDQMSISNEGMELTVSVLEAKGLICP---FSVESLDTFVRIYLV 531
            .....::  .:..|.:|..|...|.|:.....:.|::|...||...|   ||..| |.||::||:
Zfish   370 LSPGSEE--EEHEGPVCEKLGRIQFSVGYSFQDSTLTVKILKGQDLPAKDFSGTS-DPFVKLYLL 431

  Fly   532 PDHPGAMQTKVVKGTLTPSYNESFDF--WLHKRQARHSLWFHL--YHNGPAHTLIGEAEMEIG-- 590
            ||....::|||.:..|.|.:||:|.|  :.:::..:.:|:..:  |.....:..|||..:.:.
Zfish   432 PDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRTLYLQVLDYDRFSRNDPIGEVSIPLNKV 496

  Fly   591 EMPRPITTWIPLSDSRKCNARWGELMFSLSYLPTAERLTIVVVKARNLK-LD-GEQPAPESAETV 653
            |:....|.|..|......:...|:|:.||.|.|||..:|:.::|||||| :| |....|
Zfish   497 ELVPMQTLWKELKPCSDGSGSRGDLLVSLCYNPTANIITVSIIKARNLKAMDIGGTSDP------ 555

  Fly   654 HSVFVKVYLMDKDRKVLKKRTSLKRKDRSPIFNESMIFSVPPPSLTTTQLRVTVFG---VTTSGV 715
               :|||:||:||::|.||:|.:.::..:|:||||..|.||...|..|.:.:||..   ::.:.|
Zfish   556 ---YVKVWLMNKDKRVEKKKTVVMKRCLNPVFNESFPFDVPAHVLRETTIVITVMDKDRLSRNDV 617

  Fly   716 TPLGHIVAGSCAVGKGLRHWHQMLSSLRKPVAMWHVLR 753
              :|.|.....:....::||..|:|..|..||.||.|:
Zfish   618 --IGKIYLSWKSGPAEVKHWKDMMSHPRTAVAQWHALK 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt12	NP_572878.1	C2	503..602	CDD:425499	32/107 (30%)
		C2B_Synaptotagmin-12	612..753	CDD:176051	53/145 (37%)
syt7b	XP_068078246.1	C2A_Synaptotagmin-7	386..510	CDD:176032	36/124 (29%)
		C2B_Synaptotagmin-7	518..653	CDD:176050	53/145 (37%)