| Sequence 1: | NP_572873.2 | Gene: | IP3K2 / 32285 | FlyBaseID: | FBgn0283680 | Length: | 691 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002212.3 | Gene: | ITPKB / 3707 | HGNCID: | 6179 | Length: | 946 | Species: | Homo sapiens |
| Alignment Length: | 795 | Identity: | 282/795 - (35%) |
|---|---|---|---|
| Similarity: | 369/795 - (46%) | Gaps: | 187/795 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MIVQ--QQQQQQLSNEGE--PKTL---------PGATASNSDEGCNVTGGGLSPYSSDNEDNSLS 52
Fly 53 PRQRK--MKVTRCASSDSALGLDVDDGGMDVP-----LPPQRRM---TLTV-TDL--------PL 98
Fly 99 RPALLPLAEPTA--------LPDSPL-----------TSPT-GGGNPSVGVPTKVLLEERVVAAP 143
Fly 144 GSRRESTQSSYSELGVSGLPLGVRYVRTPSV-------VVSDYSDDITACGISMEEMEYFRLQRA 201
Fly 202 RG-----QRRCSLEAGHHSHSGGH---GAHGHGGS---GAAGMSPGCGKDDGQSDVSAASSCSNL 255
Fly 256 Y---------------YC--GSTISALDGGECIVNGV--RVALARKSSTQSSSLSDEEEEEEDDD 301
Fly 302 ---------EDRDE-----------------QDRDEDDRDAEEMLQ------------------- 321
Fly 322 -------EDYERGDRERERERQISELMAATQLGDRQRDRSKKSSGWRKIRNIVQWTPFFQTYKKQ 379
Fly 380 RYPWVQLAGHQGNFKAGPEPGTVLKKLCPKEEECFQILMHDLLRPYVPVYKGQVTSEDGELYLQL 444
Fly 445 QDLLSDYVQPCVMDCKVGVRTYLEEELSKAKEKPKLRKDMYDKMIQIDSHAPTAEEHAAKAVTKP 509
Fly 510 RYMVWRETISSTATLGFRIEGIKKSDGTSSKDFKTTKSREQIKLAFLEFLSGHPHILPRYIQRLR 574
Fly 575 AIRATLAVSEFFQTHEVIGSSLLFVHD-QTHASIWLIDFAKTVELPPQLRIDHYSAWKVGNHEDG 638
Fly 639 YLIGINNLIDIFVEL 653 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| IP3K2 | NP_572873.2 | IPK | 441..650 | CDD:281727 | 135/209 (65%) |
| ITPKB | NP_002212.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 19..128 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 156..288 | 21/100 (21%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 308..472 | 46/199 (23%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 486..561 | 13/74 (18%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 580..638 | 10/58 (17%) | |||
| IPK | 726..937 | CDD:281727 | 136/210 (65%) | ||
| Calmodulin-binding. /evidence=ECO:0000250 | 768..776 | 6/7 (86%) | |||
| Substrate binding. /evidence=ECO:0000250 | 793..800 | 5/6 (83%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 285 | 1.000 | Domainoid score | I1620 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 1 | 1.000 | - | - | H1672 | |
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D410791at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001484 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41776 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_103318 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR12400 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R10451 |
| SonicParanoid | 1 | 1.000 | - | - | X1215 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 10 | 9.950 | |||||