DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment IP3K2 and IP3K1

DIOPT Version :9

Sequence 1:	NP_572873.2	Gene:	IP3K2 / 32285	FlyBaseID:	FBgn0283680	Length:	691	Species:	Drosophila melanogaster
Sequence 2:	NP_609313.2	Gene:	IP3K1 / 34300	FlyBaseID:	FBgn0032147	Length:	441	Species:	Drosophila melanogaster

Alignment Length:	418	Identity:	144/418 - (34%)
Similarity:	213/418 - (50%)	Gaps:	64/418 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 CIVN-GVR-----VAL-ARKSSTQSSSLSDEEEEEEDDDEDRDEQDRDEDDRDAEEMLQEDYERG 327
            ||.| |::     :|| ...||.|.|::..|.|:::      .:|.:.:.:.:.|.:..|:.:..
  Fly    45 CIDNIGLKQLWKLIALDTSASSKQRSAMMLEVEQQQ------QQQQQQQSNNNNERIPNENCDYL 103

  Fly   328 DRERERERQISELMAATQLGDRQRDRSKKSSGWRKIRNIVQWTPFF---QTYKKQRYP--WVQLA 387
            ..:|..:...:.:.|.    |..:....|......:......||..   |...||..|  |:||:
  Fly   104 SLQRSGQAPKNHIQAQ----DPAQMSLLKFLAINALELSAPATPHLLQHQQAHKQAKPQGWMQLS 164

  Fly   388 GHQGNFKAGPE------PGTVLKK--------------LCPKEEECFQILMHDLLRPYVPVYKGQ 432
            ||       ||      .|.|.|:              :| ||.:..||         ||.|.|
  Fly   165 GH-------PESIVPTSTGIVRKRISGLEDSEVHAYRLIC-KEPQTAQI---------VPAYFG- 211

  Fly   433 VTSEDGELYLQLQDLLSDYVQPCVMDCKVGVRTYLEEELSKAKEKPKLRKDMYDKMIQIDSHAPT 497
            :.....:.:::|||||:.:..|||||.|:|.||:||.|:|.|    .||.|:|.|||.:|:.|||
  Fly   212 IQEMQSQHFIELQDLLAGFRDPCVMDIKMGSRTFLESEVSNA----TLRPDLYQKMIAVDAGAPT 272

  Fly   498 AEEHAAKAVTKPRYMVWRETISSTATLGFRIEGIKKSDGTSSKDFKTTKSREQIKLAFLEFLSGH 562
            ..||.|:|:||.|||.:||::||:.:.|||||.::.......||.||.:|.|||.....:||:..
  Fly   273 PAEHEARAITKLRYMTFRESLSSSHSKGFRIEALRLRGRPPVKDLKTCRSSEQIAQTIEQFLAAR 337

  Fly   563 PHILPRYIQRLRAIRATLAVSEFFQTHEVIGSSLLFVHDQTHASIWLIDFAKTVELPPQLRIDHY 627
            ..:....::||:.:|..:..|.||.:||:||||:..|:|.....:|||||||..||||.:|:||.
  Fly   338 RSVQKELLKRLKHMRLVIEQSTFFASHEIIGSSIFIVYDDDRVGVWLIDFAKCRELPPHVRVDHR 402

  Fly   628 SAWKVGNHEDGYLIGINNLIDIFVELQA 655
            |||..||.|:|.|.|::.||..|.|:.|
  Fly   403 SAWAPGNREEGLLRGMDELIRSFEEVYA 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
IP3K2	NP_572873.2	IPK	441..650	CDD:281727	97/208 (47%)
IP3K1	NP_609313.2	IPK	220..426	CDD:281727	97/209 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455381
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4475
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D410791at33208
OrthoFinder	1	1.000	-	-		FOG0001484
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103318
Panther	1	1.100	-	-	P	PTHR12400
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1215
	8	7.800